ENSG00000225697


Homo sapiens

Features
Gene ID: ENSG00000225697
  
Biological name :SLC26A6
  
Synonyms : Q9BXS9 / SLC26A6 / solute carrier family 26 member 6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: -1
Band: p21.31
Gene start: 48625723
Gene end: 48635493
  
Corresponding Affymetrix probe sets: 221572_s_at (Human Genome U133 Plus 2.0 Array)   232551_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000401813
Ensembl peptide - ENSP00000404684
Ensembl peptide - ENSP00000405872
Ensembl peptide - ENSP00000378920
Ensembl peptide - ENSP00000373239
Ensembl peptide - ENSP00000351597
Ensembl peptide - ENSP00000337648
Ensembl peptide - ENSP00000307089
Ensembl peptide - ENSP00000401066
Ensembl peptide - ENSP00000404607
Ensembl peptide - ENSP00000387532
Ensembl peptide - ENSP00000388721
Ensembl peptide - ENSP00000389922
NCBI entrez gene - 65010     See in Manteia.
OMIM - 610068
RefSeq - NM_001281733
RefSeq - NM_134263
RefSeq - NM_134426
RefSeq - NM_001040454
RefSeq - NM_001281732
RefSeq - NM_022911
RefSeq Peptide - NP_001268662
RefSeq Peptide - NP_001268661
RefSeq Peptide - NP_001035544
RefSeq Peptide - NP_602298
RefSeq Peptide - NP_599025
RefSeq Peptide - NP_075062
swissprot - Q9BXS9
swissprot - A0A0C4DFT5
swissprot - C9J6Y3
swissprot - C9JKR6
swissprot - F8W9I8
swissprot - G3XAC1
swissprot - H7BZ36
swissprot - H7BZB1
swissprot - H7BZJ6
swissprot - H7C291
Ensembl - ENSG00000225697
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:ch211-117c9.2ENSDARG00000058738Danio rerio
 slc26a6ENSDARG00000097292Danio rerio
 slc26a6ENSDARG00000055835Danio rerio
 slc26a6lENSDARG00000054127Danio rerio
 SLC26A6ENSGALG00000026089Gallus gallus
 Slc26a6ENSMUSG00000023259Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P58743 / SLC26A5 / solute carrier family 26 member 5ENSG0000017061538
O43511 / SLC26A4 / solute carrier family 26 member 4ENSG0000009113737
P40879 / SLC26A3 / solute carrier family 26 member 3ENSG0000009113836
Q7LBE3 / SLC26A9 / solute carrier family 26 member 9ENSG0000017450234
Q9H2B4 / SLC26A1 / solute carrier family 26 member 1ENSG0000014521731
P50443 / SLC26A2 / solute carrier family 26 member 2ENSG0000015585030
Q96RN1 / SLC26A8 / solute carrier family 26 member 8ENSG0000011205329
Q8TE54 / SLC26A7 / solute carrier family 26 member 7ENSG0000014760624
Q8NG04 / SLC26A10 / solute carrier family 26 member 10ENSG0000013550223


Protein motifs (from Interpro)
Interpro ID Name
 IPR001902  SLC26A/SulP transporter
 IPR002645  STAS domain
 IPR011547  SLC26A/SulP transporter domain
 IPR018045  Sulphate anion transporter, conserved site
 IPR030323  Solute carrier family 26 member 6
 IPR036513  STAS domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport TAS
 biological_processGO:0006820 anion transport IEA
 biological_processGO:0006821 chloride transport IMP
 biological_processGO:0008272 sulfate transport IEA
 biological_processGO:0015701 bicarbonate transport IMP
 biological_processGO:0015724 formate transport ISS
 biological_processGO:0015797 mannitol transport ISS
 biological_processGO:0019532 oxalate transport ISS
 biological_processGO:0030321 transepithelial chloride transport ISS
 biological_processGO:0042045 epithelial fluid transport ISS
 biological_processGO:0042391 regulation of membrane potential IBA
 biological_processGO:0046724 oxalic acid secretion ISS
 biological_processGO:0048240 sperm capacitation ISS
 biological_processGO:0050892 intestinal absorption ISS
 biological_processGO:0051453 regulation of intracellular pH IMP
 biological_processGO:0051454 intracellular pH elevation IEA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0070633 transepithelial transport ISS
 biological_processGO:0071320 cellular response to cAMP ISS
 biological_processGO:0071332 cellular response to fructose stimulus ISS
 biological_processGO:0071346 cellular response to interferon-gamma IDA
 biological_processGO:0098656 anion transmembrane transport IEA
 biological_processGO:1902358 sulfate transmembrane transport IEA
 biological_processGO:1902476 chloride transmembrane transport IEA
 biological_processGO:2001150 positive regulation of dipeptide transmembrane transport ISS
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0012506 vesicle membrane ISS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016323 basolateral plasma membrane IEA
 cellular_componentGO:0016324 apical plasma membrane IEA
 cellular_componentGO:0030659 cytoplasmic vesicle membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0031526 brush border membrane IDA
 cellular_componentGO:0031982 vesicle ISS
 cellular_componentGO:0034707 chloride channel complex IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 cellular_componentGO:0097225 sperm midpiece ISS
 molecular_functionGO:0005254 chloride channel activity IBA
 molecular_functionGO:0005452 inorganic anion exchanger activity TAS
 molecular_functionGO:0008271 secondary active sulfate transmembrane transporter activity IEA
 molecular_functionGO:0008509 anion transmembrane transporter activity IEA
 molecular_functionGO:0015106 bicarbonate transmembrane transporter activity ISS
 molecular_functionGO:0015108 chloride transmembrane transporter activity ISS
 molecular_functionGO:0015116 sulfate transmembrane transporter activity IEA
 molecular_functionGO:0015297 antiporter activity IEA
 molecular_functionGO:0015301 anion:anion antiporter activity IEA
 molecular_functionGO:0015499 formate transmembrane transporter activity ISS
 molecular_functionGO:0015562 efflux transmembrane transporter activity ISS
 molecular_functionGO:0015660 formate efflux transmembrane transporter activity ISS
 molecular_functionGO:0019531 oxalate transmembrane transporter activity IMP
 molecular_functionGO:0030165 PDZ domain binding ISS


Pathways (from Reactome)
Pathway description
Multifunctional anion exchangers


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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