ENSMUSG00000023259


Mus musculus

Features
Gene ID: ENSMUSG00000023259
  
Biological name :Slc26a6
  
Synonyms : Slc26a6 / solute carrier family 26, member 6
  
Possible biological names infered from orthology : Q9BXS9
  
Species: Mus musculus
  
Chr. number: 9
Strand: 1
Band: F2
Gene start: 108853283
Gene end: 108913049
  
Corresponding Affymetrix probe sets: 10589166 (MoGene1.0st)   10589190 (MoGene1.0st)   1416275_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000140982
Ensembl peptide - ENSMUSP00000142250
Ensembl peptide - ENSMUSP00000141632
Ensembl peptide - ENSMUSP00000141409
Ensembl peptide - ENSMUSP00000141336
Ensembl peptide - ENSMUSP00000095979
Ensembl peptide - ENSMUSP00000140849
NCBI entrez gene - 171429     See in Manteia.
MGI - MGI:2159728
RefSeq - NM_134420
RefSeq Peptide - NP_599252
swissprot - A0A0A6YWP3
swissprot - A0A087WS07
swissprot - A0A0A0MQB3
swissprot - A0A087WSC0
Ensembl - ENSMUSG00000023259
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:ch211-117c9.2ENSDARG00000058738Danio rerio
 slc26a6ENSDARG00000097292Danio rerio
 slc26a6ENSDARG00000055835Danio rerio
 slc26a6lENSDARG00000054127Danio rerio
 SLC26A6ENSGALG00000026089Gallus gallus
 Q9BXS9ENSG00000225697Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q99NH7 / Slc26a5 / Prestin / P58743* / solute carrier family 26 member 5*ENSMUSG0000002901538
Q9R155 / Slc26a4 / Pendrin / O43511* / solute carrier family 26 member 4*ENSMUSG0000002065136
Q9WVC8 / Slc26a3 / Chloride anion exchanger / P40879* / solute carrier family 26 member 3*ENSMUSG0000000122535
Slc26a9 / solute carrier family 26 member 9 / Q7LBE3*ENSMUSG0000004226833
P58735 / Slc26a1 / solute carrier family 26 (sulfate transporter), member 1 / Q9H2B4* / solute carrier family 26 member 1*ENSMUSG0000004695931
Slc26a10 / solute carrier family 26 member 10 / Q8NG04*ENSMUSG0000004044129
Q62273 / Slc26a2 / Sulfate transporter / P50443* / solute carrier family 26 member 2*ENSMUSG0000003432029
Q8R0C3 / Slc26a8 / Testis anion transporter 1 / Q96RN1* / solute carrier family 26 member 8*ENSMUSG0000003619628
Q8R2Z3 / Slc26a7 / Anion exchange transporter / Q8TE54* / solute carrier family 26 member 7*ENSMUSG0000004056924


Protein motifs (from Interpro)
Interpro ID Name
 IPR001902  SLC26A/SulP transporter
 IPR011547  SLC26A/SulP transporter domain
 IPR018045  Sulphate anion transporter, conserved site
 IPR030323  Solute carrier family 26 member 6
 IPR036513  STAS domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006820 anion transport IEA
 biological_processGO:0006821 chloride transport IEA
 biological_processGO:0008272 sulfate transport IEA
 biological_processGO:0015701 bicarbonate transport IEA
 biological_processGO:0019532 oxalate transport IEA
 biological_processGO:0030321 transepithelial chloride transport IEA
 biological_processGO:0051453 regulation of intracellular pH IEA
 biological_processGO:0051454 intracellular pH elevation IEA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0071346 cellular response to interferon-gamma IEA
 biological_processGO:0098656 anion transmembrane transport IEA
 biological_processGO:1902358 sulfate transmembrane transport IEA
 biological_processGO:1902476 chloride transmembrane transport IEA
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016323 basolateral plasma membrane IEA
 cellular_componentGO:0016324 apical plasma membrane IEA
 cellular_componentGO:0031526 brush border membrane IEA
 molecular_functionGO:0008271 secondary active sulfate transmembrane transporter activity IEA
 molecular_functionGO:0008509 anion transmembrane transporter activity IEA
 molecular_functionGO:0015106 bicarbonate transmembrane transporter activity IEA
 molecular_functionGO:0015108 chloride transmembrane transporter activity IEA
 molecular_functionGO:0015116 sulfate transmembrane transporter activity IEA
 molecular_functionGO:0015301 anion:anion antiporter activity IEA
 molecular_functionGO:0019531 oxalate transmembrane transporter activity IEA


Pathways (from Reactome)
Pathway description
Multifunctional anion exchangers


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001663 abnormal digestive system physiology "altered function of the organ system that converts ingested food to nutrients and energy" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Il6tm1Poli/Il6tm1Poli
Genetic Background: involves: 129S/SvEv * C57BL/6

Allelic Composition: Slc26a6tm1Sole/Slc26a6tm1Sole
Genetic Background: involves: 129S6/SvEvTac

 MP:0002136 abnormal kidney physiology "altered ability or inability to excrete urine, not due to anatomical defect" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Il6tm1Poli/Il6tm1Poli
Genetic Background: involves: 129S/SvEv * C57BL/6

 MP:0002693 abnormal pancreas physiology "abberrant function of the organ that secretes pancreatic juice into the duodenum and secretes glucagon and insulin into the bloodstream" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Gtf2iGt(RRI105)Byg/Gtf2iGt(RRI105)Byg
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0002694 abnormal pancreas secretion "altered ability of the pancreas to release its products" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Gtf2iGt(RRI105)Byg/Gtf2iGt(RRI105)Byg
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0005360 urolithiasis "presence of calculi in any part of the urinary system" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:85461, J:85462]
Show

Allelic Composition: Tor1atm1Wtd/Tor1atm2Wtd
Genetic Background: involves: 129S1/Sv

 MP:0009642 abnormal blood homeostasis "anomaly in the processes involved in the maintenance of an internal equilibrium of various functions or chemical or protein composition of the blood" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Tor1atm1Wtd/Tor1atm2Wtd
Genetic Background: involves: 129S1/Sv

 MP:0009643 abnormal urine homeostasis "anomaly in the processes involved in the maintenance of an internal equilibrium of various functions and chemical or protein composition of the urine" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Tor1atm1Wtd/Tor1atm2Wtd
Genetic Background: involves: 129S1/Sv

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr