ENSG00000229183


Homo sapiens

Features
Gene ID: ENSG00000229183
  
Biological name :PGA4
  
Synonyms : P0DJD7 / pepsinogen 4, group I (pepsinogen A) / PGA4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: 1
Band: q12.2
Gene start: 61222216
Gene end: 61231927
  
Corresponding Affymetrix probe sets: 213265_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000442757
Ensembl peptide - ENSP00000443623
Ensembl peptide - ENSP00000367391
NCBI entrez gene - 643847     See in Manteia.
OMIM - 169720
RefSeq - NM_001079808
RefSeq Peptide - NP_001073276
swissprot - A0A1S5UZ02
swissprot - F5GXL4
swissprot - F5H0H6
swissprot - P0DJD7
Ensembl - ENSG00000229183
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PGA3ENSDARG00000099824Danio rerio
 PGA5ENSGALG00000039242Gallus gallus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PGA3 / P0DJD8 / pepsinogen 3, group I (pepsinogen A)ENSG00000229859100
PGA5 / P0DJD9 / pepsinogen 5, group I (pepsinogen A)ENSG0000025671399
CTSE / P14091 / cathepsin EENSG0000019618854
PGC / P20142 / progastricsinENSG0000009608851
CTSD / P07339 / cathepsin DENSG0000011798446
NAPSA / O96009 / napsin A aspartic peptidaseENSG0000013140041
AC068580.4ENSG0000025064440
REN / renin / P00797ENSG0000014383937


Protein motifs (from Interpro)
Interpro ID Name
 IPR001461  Aspartic peptidase A1 family
 IPR001969  Aspartic peptidase, active site
 IPR012848  Aspartic peptidase, N-terminal
 IPR021109  Aspartic peptidase domain superfamily
 IPR033121  Peptidase family A1 domain
 IPR034162  Pepsin catalytic domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0006914 autophagy IBA
 biological_processGO:0007586 digestion IEA
 biological_processGO:0030163 protein catabolic process IBA
 biological_processGO:0044267 cellular protein metabolic process TAS
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:0097486 multivesicular body lumen TAS
 molecular_functionGO:0004190 aspartic-type endopeptidase activity IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Surfactant metabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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