ENSG00000196188


Homo sapiens

Features
Gene ID: ENSG00000196188
  
Biological name :CTSE
  
Synonyms : cathepsin E / CTSE / P14091
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: q32.1
Gene start: 206009264
Gene end: 206023909
  
Corresponding Affymetrix probe sets: 205927_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000350911
Ensembl peptide - ENSP00000353350
NCBI entrez gene - 1510     See in Manteia.
OMIM - 116890
RefSeq - XM_011509245
RefSeq - NM_001317331
RefSeq - NM_001910
RefSeq - NM_148964
RefSeq - XM_011509244
RefSeq Peptide - NP_683865
RefSeq Peptide - NP_001304260
RefSeq Peptide - NP_001901
swissprot - P14091
Ensembl - ENSG00000196188
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PGA3ENSDARG00000099824Danio rerio
 CTSEENSGALG00000000786Gallus gallus
 CtseENSMUSG00000004552Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PGA4 / P0DJD7 / pepsinogen 4, group I (pepsinogen A)ENSG0000022918353
PGA5 / P0DJD9 / pepsinogen 5, group I (pepsinogen A)ENSG0000025671353
PGA3 / P0DJD8 / pepsinogen 3, group I (pepsinogen A)ENSG0000022985953
CTSD / P07339 / cathepsin DENSG0000011798446
PGC / P20142 / progastricsinENSG0000009608845
NAPSA / O96009 / napsin A aspartic peptidaseENSG0000013140044
AC068580.4ENSG0000025064441
REN / renin / P00797ENSG0000014383938


Protein motifs (from Interpro)
Interpro ID Name
 IPR001461  Aspartic peptidase A1 family
 IPR001969  Aspartic peptidase, active site
 IPR012848  Aspartic peptidase, N-terminal
 IPR021109  Aspartic peptidase domain superfamily
 IPR033121  Peptidase family A1 domain
 IPR033145  Cathepsin E


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0016540 protein autoprocessing IEA
 biological_processGO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II IDA
 biological_processGO:0030163 protein catabolic process IBA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0004190 aspartic-type endopeptidase activity IDA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA


Pathways (from Reactome)
Pathway description
MHC class II antigen presentation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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