ENSG00000096088


Homo sapiens

Features
Gene ID: ENSG00000096088
  
Biological name :PGC
  
Synonyms : P20142 / PGC / progastricsin
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: -1
Band: p21.1
Gene start: 41736711
Gene end: 41754109
  
Corresponding Affymetrix probe sets: 1555236_a_at (Human Genome U133 Plus 2.0 Array)   205261_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000399429
Ensembl peptide - ENSP00000405094
Ensembl peptide - ENSP00000349094
Ensembl peptide - ENSP00000362116
NCBI entrez gene - 5225     See in Manteia.
OMIM - 169740
RefSeq - NM_002630
RefSeq - NM_001166424
RefSeq Peptide - NP_001159896
RefSeq Peptide - NP_002621
swissprot - Q4VXA6
swissprot - P20142
swissprot - A2A3L9
Ensembl - ENSG00000096088
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PGA3ENSDARG00000099824Danio rerio
 PGCENSGALG00000028489Gallus gallus
 PgcENSMUSG00000023987Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PGA5 / P0DJD9 / pepsinogen 5, group I (pepsinogen A)ENSG0000025671351
PGA4 / P0DJD7 / pepsinogen 4, group I (pepsinogen A)ENSG0000022918351
PGA3 / P0DJD8 / pepsinogen 3, group I (pepsinogen A)ENSG0000022985951
CTSE / P14091 / cathepsin EENSG0000019618846
CTSD / P07339 / cathepsin DENSG0000011798440
NAPSA / O96009 / napsin A aspartic peptidaseENSG0000013140038
AC068580.4ENSG0000025064435
REN / renin / P00797ENSG0000014383934


Protein motifs (from Interpro)
Interpro ID Name
 IPR001461  Aspartic peptidase A1 family
 IPR001969  Aspartic peptidase, active site
 IPR012848  Aspartic peptidase, N-terminal
 IPR021109  Aspartic peptidase domain superfamily
 IPR033121  Peptidase family A1 domain
 IPR033735  Gastricsin


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002803 positive regulation of antibacterial peptide production IMP
 biological_processGO:0006508 proteolysis TAS
 biological_processGO:0006914 autophagy IBA
 biological_processGO:0007586 digestion IEA
 biological_processGO:0030163 protein catabolic process IBA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0004190 aspartic-type endopeptidase activity TAS
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr