ENSMUSG00000023987


Mus musculus

Features
Gene ID: ENSMUSG00000023987
  
Biological name :Pgc
  
Synonyms : Gastricsin / Pgc / Q9D7R7
  
Possible biological names infered from orthology : P20142 / progastricsin
  
Species: Mus musculus
  
Chr. number: 17
Strand: 1
Band: C
Gene start: 47726842
Gene end: 47734482
  
Corresponding Affymetrix probe sets: 10445718 (MoGene1.0st)   1415786_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000123459
Ensembl peptide - ENSMUSP00000024782
NCBI entrez gene - 109820     See in Manteia.
MGI - MGI:98909
RefSeq - NM_025973
RefSeq Peptide - NP_080249
swissprot - D3YZ92
swissprot - Q9D7R7
Ensembl - ENSMUSG00000023987
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PGA3ENSDARG00000099824Danio rerio
 PGCENSGALG00000028489Gallus gallus
 PGCENSG00000096088Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Ctse / P70269 / cathepsin E / P14091*ENSMUSG0000000455246
Pga5 / Q9D106 / Pepsin A-5 ENSMUSG0000002473842
Ctsd / P18242 / cathepsin D / P07339* / AC068580.4*ENSMUSG0000000789142
Cym / chymosinENSMUSG0000004621341
Napsa / O09043 / Napsin-A / O96009* / napsin A aspartic peptidase*ENSMUSG0000000220438
Ren1 / P06281 / Mus musculus renin 2 tandem duplication of Ren1 (Ren2), mRNA. / REN* / renin* / P00797*ENSMUSG0000007064535
AC034099.1 / CTSD* / P07339* / AC068580.4* / cathepsin D*ENSMUSG0000011004022


Protein motifs (from Interpro)
Interpro ID Name
 IPR001461  Aspartic peptidase A1 family
 IPR001969  Aspartic peptidase, active site
 IPR012848  Aspartic peptidase, N-terminal
 IPR021109  Aspartic peptidase domain superfamily
 IPR033121  Peptidase family A1 domain
 IPR033735  Gastricsin


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002803 positive regulation of antibacterial peptide production IEA
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0006914 autophagy IBA
 biological_processGO:0007586 digestion IEA
 biological_processGO:0030163 protein catabolic process IBA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IEA
 molecular_functionGO:0004190 aspartic-type endopeptidase activity IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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