ENSG00000250506


Homo sapiens

Features
Gene ID: ENSG00000250506
  
Biological name :CDK3
  
Synonyms : CDK3 / cyclin dependent kinase 3 / Q00526
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: 1
Band: q25.1
Gene start: 76000906
Gene end: 76005999
  
Corresponding Affymetrix probe sets: 207188_at (Human Genome U133 Plus 2.0 Array)   229468_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000465062
Ensembl peptide - ENSP00000466237
Ensembl peptide - ENSP00000400088
Ensembl peptide - ENSP00000410561
NCBI entrez gene - 1018     See in Manteia.
OMIM - 123828
RefSeq - NM_001258
RefSeq Peptide - NP_001249
swissprot - K7EJ83
swissprot - K7ELV5
swissprot - Q00526
Ensembl - ENSG00000250506
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000038535Gallus gallus
 CDK3ENSGALG00000008462Gallus gallus
 Cdk3-psENSMUSG00000092300Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CDK2 / P24941 / cyclin dependent kinase 2ENSG0000012337473
CDK1 / P06493 / cyclin dependent kinase 1ENSG0000017031263
CDK5 / Q00535 / cyclin dependent kinase 5ENSG0000016488558
CDK6 / Q00534 / cyclin dependent kinase 6ENSG0000010581046
CDK11B / cyclin dependent kinase 11BENSG0000024833345
CDK11A / Q9UQ88 / cyclin dependent kinase 11AENSG0000000812845
CDK10 / Q15131 / cyclin dependent kinase 10ENSG0000018532444
CDK4 / P11802 / cyclin dependent kinase 4ENSG0000013544644


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000082 G1/S transition of mitotic cell cycle TAS
 biological_processGO:0006468 protein phosphorylation IBA
 biological_processGO:0006974 cellular response to DNA damage stimulus IDA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007165 signal transduction IBA
 biological_processGO:0007275 multicellular organism development IBA
 biological_processGO:0008283 cell proliferation TAS
 biological_processGO:0008284 positive regulation of cell proliferation IBA
 biological_processGO:0010033 response to organic substance IBA
 biological_processGO:0010389 regulation of G2/M transition of mitotic cell cycle IBA
 biological_processGO:0010468 regulation of gene expression IBA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0045023 G0 to G1 transition TAS
 biological_processGO:0051301 cell division IEA
 cellular_componentGO:0000307 cyclin-dependent protein kinase holoenzyme complex IBA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0004693 cyclin-dependent protein serine/threonine kinase activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0030332 cyclin binding IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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