ENSG00000008128


Homo sapiens

Features
Gene ID: ENSG00000008128
  
Biological name :CDK11A
  
Synonyms : CDK11A / cyclin dependent kinase 11A / Q9UQ88
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: p36.33
Gene start: 1702730
Gene end: 1724324
  
Corresponding Affymetrix probe sets: 207428_x_at (Human Genome U133 Plus 2.0 Array)   210474_s_at (Human Genome U133 Plus 2.0 Array)   211289_x_at (Human Genome U133 Plus 2.0 Array)   212401_s_at (Human Genome U133 Plus 2.0 Array)   215329_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000384442
Ensembl peptide - ENSP00000422149
Ensembl peptide - ENSP00000462289
Ensembl peptide - ENSP00000423900
Ensembl peptide - ENSP00000348529
Ensembl peptide - ENSP00000350403
Ensembl peptide - ENSP00000351629
Ensembl peptide - ENSP00000367900
Ensembl peptide - ENSP00000367905
Ensembl peptide - ENSP00000383874
NCBI entrez gene - 728642     See in Manteia.
OMIM - 116951
RefSeq - NM_001313982
RefSeq - NM_024011
RefSeq - NM_033529
RefSeq - NM_001313896
RefSeq Peptide - NP_001300825
RefSeq Peptide - NP_076916
RefSeq Peptide - NP_277071
RefSeq Peptide - NP_001300911
swissprot - Q9UQ88
swissprot - E7ESP2
swissprot - J3KS35
swissprot - Q5QPQ9
swissprot - Q5QPR3
swissprot - Q5QPR4
swissprot - E9PFJ2
Ensembl - ENSG00000008128
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cdk11bENSDARG00000102546Danio rerio
 CDK11AENSGALG00000001382Gallus gallus
 Cdk11bENSMUSG00000029062Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CDK11B / cyclin dependent kinase 11BENSG0000024833399
CDK10 / Q15131 / cyclin dependent kinase 10ENSG0000018532424
CDK2 / P24941 / cyclin dependent kinase 2ENSG0000012337417
CDK3 / Q00526 / cyclin dependent kinase 3ENSG0000025050617
CDK1 / P06493 / cyclin dependent kinase 1ENSG0000017031216
CDK5 / Q00535 / cyclin dependent kinase 5ENSG0000016488516
CDK6 / Q00534 / cyclin dependent kinase 6ENSG0000010581016
CDK4 / P11802 / cyclin dependent kinase 4ENSG0000013544615


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000278 mitotic cell cycle NAS
 biological_processGO:0001558 regulation of cell growth IEP
 biological_processGO:0006355 regulation of transcription, DNA-templated NAS
 biological_processGO:0006468 protein phosphorylation IDA
 biological_processGO:0006915 apoptotic process NAS
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007346 regulation of mitotic cell cycle IBA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0050684 regulation of mRNA processing IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity NAS
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0004693 cyclin-dependent protein serine/threonine kinase activity IBA
 molecular_functionGO:0005524 ATP binding IDA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
Recruitment of mitotic centrosome proteins and complexes


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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