ENSG00000256660


Homo sapiens

Features
Gene ID: ENSG00000256660
  
Biological name :CLEC12B
  
Synonyms : CLEC12B / C-type lectin domain family 12 member B / Q2HXU8
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: 1
Band: p13.2
Gene start: 10010627
Gene end: 10018619
  
Corresponding Affymetrix probe sets: 231357_at (Human Genome U133 Plus 2.0 Array)   231600_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000444909
Ensembl peptide - ENSP00000344563
Ensembl peptide - ENSP00000379759
Ensembl peptide - ENSP00000439561
NCBI entrez gene - 387837     See in Manteia.
OMIM - 617573
RefSeq - XM_017019295
RefSeq - NM_001129998
RefSeq - NM_001319241
RefSeq - NM_001319242
RefSeq - NM_205852
RefSeq - XM_011520658
RefSeq - XM_011520663
RefSeq Peptide - NP_995324
RefSeq Peptide - NP_001306171
RefSeq Peptide - NP_001306170
RefSeq Peptide - NP_001123470
swissprot - F5H4H7
swissprot - Q2HXU8
swissprot - A0A140VK10
Ensembl - ENSG00000256660
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Clec12bENSMUSG00000030158Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q5QGZ9 / CLEC12A / C-type lectin domain family 12 member AENSG0000017232232
CLEC1A / Q8NC01 / C-type lectin domain family 1 member AENSG0000015004831
CLEC1B / Q9P126 / C-type lectin domain family 1 member BENSG0000016568227
OLR1 / P78380 / oxidized low density lipoprotein receptor 1ENSG0000017339126
CLEC7A / Q9BXN2 / C-type lectin domain containing 7AENSG0000017224325
CLEC9A / Q6UXN8 / C-type lectin domain containing 9AENSG0000019799225


Protein motifs (from Interpro)
Interpro ID Name
 IPR001304  C-type lectin-like
 IPR013600  Ly49-like, N-terminal
 IPR016186  C-type lectin-like/link domain superfamily
 IPR016187  C-type lectin fold
 IPR033992  Natural killer cell receptor-like, C-type lectin-like domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002769 natural killer cell inhibitory signaling pathway IMP
 biological_processGO:0045953 negative regulation of natural killer cell mediated cytotoxicity IMP
 biological_processGO:2000272 negative regulation of signaling receptor activity IMP
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0009897 external side of plasma membrane IMP
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0032991 protein-containing complex IMP
 molecular_functionGO:0019903 protein phosphatase binding IPI
 molecular_functionGO:0030246 carbohydrate binding IEA
 molecular_functionGO:0030547 receptor inhibitor activity IMP


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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