ENSG00000173391


Homo sapiens

Features
Gene ID: ENSG00000173391
  
Biological name :OLR1
  
Synonyms : OLR1 / oxidized low density lipoprotein receptor 1 / P78380
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: -1
Band: p13.2
Gene start: 10158301
Gene end: 10172138
  
Corresponding Affymetrix probe sets: 210004_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000442389
Ensembl peptide - ENSP00000445085
Ensembl peptide - ENSP00000444457
Ensembl peptide - ENSP00000444068
Ensembl peptide - ENSP00000309124
Ensembl peptide - ENSP00000340572
Ensembl peptide - ENSP00000405116
Ensembl peptide - ENSP00000438744
Ensembl peptide - ENSP00000438925
Ensembl peptide - ENSP00000439251
NCBI entrez gene - 4973     See in Manteia.
OMIM - 602601
RefSeq - NM_001172633
RefSeq - NM_002543
RefSeq - NM_001172632
RefSeq Peptide - NP_001166103
RefSeq Peptide - NP_001166104
RefSeq Peptide - NP_002534
swissprot - J3QTI8
swissprot - B7ZAN8
swissprot - P78380
swissprot - A0A024RAU0
swissprot - F5GZH1
swissprot - F5H001
swissprot - F5H0N6
swissprot - F5H3G7
swissprot - F5H7N8
Ensembl - ENSG00000173391
  
Related genetic diseases (OMIM): 608446 - {Myocardial infarction, susceptibility to}, 608446
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Olr1ENSMUSG00000030162Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CLEC7A / Q9BXN2 / C-type lectin domain containing 7AENSG0000017224329
CLEC1A / Q8NC01 / C-type lectin domain family 1 member AENSG0000015004826
Q2HXU8 / CLEC12B / C-type lectin domain family 12 member BENSG0000025666026
Q5QGZ9 / CLEC12A / C-type lectin domain family 12 member AENSG0000017232224
CLEC9A / Q6UXN8 / C-type lectin domain containing 9AENSG0000019799223
CLEC1B / Q9P126 / C-type lectin domain family 1 member BENSG0000016568220


Protein motifs (from Interpro)
Interpro ID Name
 IPR001304  C-type lectin-like
 IPR013600  Ly49-like, N-terminal
 IPR016186  C-type lectin-like/link domain superfamily
 IPR016187  C-type lectin fold
 IPR033992  Natural killer cell receptor-like, C-type lectin-like domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0006508 proteolysis TAS
 biological_processGO:0006954 inflammatory response IEA
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0008015 blood circulation TAS
 biological_processGO:0043312 neutrophil degranulation TAS
 biological_processGO:0050900 leukocyte migration TAS
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0035579 specific granule membrane TAS
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 cellular_componentGO:0043235 receptor complex IDA
 cellular_componentGO:0045121 membrane raft IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:0070821 tertiary granule membrane TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0030246 carbohydrate binding IEA
 molecular_functionGO:0042802 identical protein binding IPI


Pathways (from Reactome)
Pathway description
Cell surface interactions at the vascular wall
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000173391 OLR1 / P78380 / oxidized low density lipoprotein receptor 1  / reaction / complex






 

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