ENSG00000273841


Homo sapiens

Features
Gene ID: ENSG00000273841
  
Biological name :TAF9
  
Synonyms : Q16594 / TAF9 / TATA-box binding protein associated factor 9
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: -1
Band: q13.2
Gene start: 69364743
Gene end: 69370013
  
Corresponding Affymetrix probe sets: 202168_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000370193
Ensembl peptide - ENSP00000421873
Ensembl peptide - ENSP00000427617
Ensembl peptide - ENSP00000427343
Ensembl peptide - ENSP00000426283
Ensembl peptide - ENSP00000425944
Ensembl peptide - ENSP00000425798
Ensembl peptide - ENSP00000217893
NCBI entrez gene - 6880     See in Manteia.
OMIM - 600822
RefSeq - NM_003187
RefSeq - NM_001015892
RefSeq Peptide - NP_001015892
RefSeq Peptide - NP_003178
swissprot - D6RGK3
swissprot - D6RIY1
swissprot - Q16594
swissprot - D6RIV9
swissprot - D6RIE8
swissprot - D6RHW1
Ensembl - ENSG00000273841
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 taf9ENSDARG00000077870Danio rerio
 TAF9ENSGALG00000004187Gallus gallus
 Ak6ENSMUSG00000078941Mus musculus
 Taf9ENSMUSG00000052293Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TAF9B / Q9HBM6 / TATA-box binding protein associated factor 9bENSG0000018732578


Protein motifs (from Interpro)
Interpro ID Name
 IPR003162  Transcription initiation factor TAFII31
 IPR009072  Histone-fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000492 box C/D snoRNP assembly IDA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006352 DNA-templated transcription, initiation IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II TAS
 biological_processGO:0006367 transcription initiation from RNA polymerase II promoter TAS
 biological_processGO:0006368 transcription elongation from RNA polymerase II promoter TAS
 biological_processGO:0006974 cellular response to DNA damage stimulus IC
 biological_processGO:0030307 positive regulation of cell growth IMP
 biological_processGO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process IDA
 biological_processGO:0042795 snRNA transcription by RNA polymerase II TAS
 biological_processGO:0043066 negative regulation of apoptotic process IMP
 biological_processGO:0043966 histone H3 acetylation IDA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IDA
 biological_processGO:0050821 protein stabilization IDA
 biological_processGO:0051123 RNA polymerase II transcriptional preinitiation complex assembly IEA
 biological_processGO:0060760 positive regulation of response to cytokine stimulus IMP
 biological_processGO:0070555 response to interleukin-1 IMP
 biological_processGO:1901796 regulation of signal transduction by p53 class mediator TAS
 biological_processGO:1902166 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator IC
 cellular_componentGO:0000124 SAGA complex IBA
 cellular_componentGO:0000125 PCAF complex IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005669 transcription factor TFIID complex IDA
 cellular_componentGO:0030914 STAGA complex IDA
 cellular_componentGO:0033276 transcription factor TFTC complex IDA
 cellular_componentGO:0070761 pre-snoRNP complex IDA
 cellular_componentGO:0071339 MLL1 complex IDA
 molecular_functionGO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly IBA
 molecular_functionGO:0002039 p53 binding IPI
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003713 transcription coactivator activity IMP
 molecular_functionGO:0004402 histone acetyltransferase activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0033613 activating transcription factor binding IPI
 molecular_functionGO:0044212 transcription regulatory region DNA binding IDA
 molecular_functionGO:0046982 protein heterodimerization activity IEA
 molecular_functionGO:0051117 ATPase binding IPI
 molecular_functionGO:0070742 C2H2 zinc finger domain binding IPI


Pathways (from Reactome)
Pathway description
HIV Transcription Initiation
RNA Polymerase II HIV Promoter Escape
Transcription of the HIV genome
HATs acetylate histones
RNA Polymerase II Pre-transcription Events
Regulation of TP53 Activity through Phosphorylation
RNA polymerase II transcribes snRNA genes
RNA Polymerase II Promoter Escape
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
RNA Polymerase II Transcription Initiation
RNA Polymerase II Transcription Initiation And Promoter Clearance


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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