ENSMUSG00000078941


Mus musculus

Features
Gene ID: ENSMUSG00000078941
  
Biological name :Ak6
  
Synonyms : Adenylate kinase isoenzyme 6 / Ak6 / Q8VCP8 / Q8VI33
  
Possible biological names infered from orthology : Q16594 / TAF9 / TATA-box binding protein associated factor 9
  
Species: Mus musculus
  
Chr. number: 13
Strand: 1
Band: D1
Gene start: 100650979
Gene end: 100666359
  
Corresponding Affymetrix probe sets: 10406898 (MoGene1.0st)   10512061 (MoGene1.0st)   1422778_at (Mouse Genome 430 2.0 Array)   1438250_s_at (Mouse Genome 430 2.0 Array)   1451509_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000140648
Ensembl peptide - ENSMUSP00000022135
Ensembl peptide - ENSMUSP00000081772
NCBI entrez gene - 108143     See in Manteia.
NCBI entrez gene - 102216272     See in Manteia.
MGI - MGI:5510732
RefSeq - NM_027592
RefSeq - NM_027139
RefSeq Peptide - NP_081415
RefSeq Peptide - NP_081868
swissprot - Q8VI33
swissprot - Q8VCP8
swissprot - A0A087WRI5
Ensembl - ENSMUSG00000078941
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 taf9ENSDARG00000077870Danio rerio
 TAF9ENSGALG00000004187Gallus gallus
 TAF9ENSG00000273841Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Taf9 / Q8VI33 / Transcription initiation factor TFIID subunit 9 / Q16594* / TATA-box binding protein associated factor 9*ENSMUSG00000052293100
Taf9b / Q6NZA9 / Transcription initiation factor TFIID subunit 9B / Q9HBM6* / TATA-box binding protein associated factor 9b*ENSMUSG0000004724273


Protein motifs (from Interpro)
Interpro ID Name
 IPR001977  Dephospho-CoA kinase
 IPR003162  Transcription initiation factor TAFII31
 IPR009072  Histone-fold
 IPR020618  Adenylate kinase isoenzyme 6
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000492 box C/D snoRNP assembly ISO
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006352 DNA-templated transcription, initiation IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0015937 coenzyme A biosynthetic process IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0030307 positive regulation of cell growth ISO
 biological_processGO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process ISO
 biological_processGO:0043066 negative regulation of apoptotic process ISO
 biological_processGO:0043966 histone H3 acetylation IBA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II ISO
 biological_processGO:0046939 nucleotide phosphorylation IEA
 biological_processGO:0050821 protein stabilization ISO
 biological_processGO:0051123 RNA polymerase II transcriptional preinitiation complex assembly IEA
 biological_processGO:0060760 positive regulation of response to cytokine stimulus ISO
 biological_processGO:0070555 response to interleukin-1 ISO
 cellular_componentGO:0000124 SAGA complex IBA
 cellular_componentGO:0000125 PCAF complex ISO
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005654 nucleoplasm ISS
 cellular_componentGO:0005669 transcription factor TFIID complex ISO
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0015030 Cajal body ISS
 cellular_componentGO:0030914 STAGA complex ISO
 cellular_componentGO:0033276 transcription factor TFTC complex ISO
 cellular_componentGO:0070761 pre-snoRNP complex ISO
 cellular_componentGO:0071339 MLL1 complex ISO
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly IBA
 molecular_functionGO:0002039 p53 binding ISO
 molecular_functionGO:0003677 DNA binding ISO
 molecular_functionGO:0003713 transcription coactivator activity ISO
 molecular_functionGO:0004017 adenylate kinase activity IEA
 molecular_functionGO:0004140 dephospho-CoA kinase activity IEA
 molecular_functionGO:0004402 histone acetyltransferase activity IBA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008134 transcription factor binding IBA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0033613 activating transcription factor binding ISO
 molecular_functionGO:0044212 transcription regulatory region DNA binding IBA
 molecular_functionGO:0046982 protein heterodimerization activity IEA
 molecular_functionGO:0051117 ATPase binding ISO
 molecular_functionGO:0070742 C2H2 zinc finger domain binding ISO


Pathways (from Reactome)
Pathway description
RNA Polymerase II Pre-transcription Events
Regulation of TP53 Activity through Phosphorylation
RNA polymerase II transcribes snRNA genes
RNA Polymerase II Promoter Escape
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
RNA Polymerase II Transcription Initiation
RNA Polymerase II Transcription Initiation And Promoter Clearance


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr