ENSGALG00000000636


Gallus gallus

Features
Gene ID: ENSGALG00000000636
  
Biological name :MDM4
  
Synonyms : MDM4 / MDM4, p53 regulator
  
Possible biological names infered from orthology : O15151 / O35618 / transformed mouse 3T3 cell double minute 4
  
Species: Gallus gallus
  
Chr. number: 26
Strand: 1
Band:
Gene start: 1802527
Gene end: 1819782
  
Corresponding Affymetrix probe sets: Gga.11983.1.S1_s_at (Chicken Array)   GgaAffx.26557.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000000906
NCBI entrez gene - 419823     See in Manteia.
RefSeq - XM_004934925
RefSeq - XM_004934926
RefSeq - XM_015299093
RefSeq - XM_015299095
RefSeq - XM_015299096
RefSeq - XM_417957
RefSeq - XM_004934924
swissprot - E1C4B0
Ensembl - ENSGALG00000000636
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mdm4ENSDARG00000057513Danio rerio
 MDM4ENSG00000198625Homo sapiens
 Mdm4ENSMUSG00000054387Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MDM2 / MDM2 proto-oncogene / P23804* / Q00987* / E3 ubiquitin-protein ligase Mdm2 *ENSGALG0000000994219


Protein motifs (from Interpro)
Interpro ID Name
 IPR001876  Zinc finger, RanBP2-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR016495  p53 negative regulator Mdm2/Mdm4


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0008283 cell proliferation IEA
 biological_processGO:0030330 DNA damage response, signal transduction by p53 class mediator IEA
 biological_processGO:0042177 negative regulation of protein catabolic process IEA
 biological_processGO:0043066 negative regulation of apoptotic process IEA
 biological_processGO:0045023 G0 to G1 transition IEA
 biological_processGO:0050821 protein stabilization IEA
 biological_processGO:0065003 protein-containing complex assembly IEA
 biological_processGO:0071157 negative regulation of cell cycle arrest IEA
 biological_processGO:0071456 cellular response to hypoxia IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0019899 enzyme binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Ub-specific processing proteases
Regulation of TP53 Activity through Phosphorylation
Regulation of TP53 Degradation
Regulation of TP53 Activity through Methylation
Stabilization of p53


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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