ENSGALG00000001051


Gallus gallus

Features
Gene ID: ENSGALG00000001051
  
Biological name :LDLRAP1
  
Synonyms : LDLRAP1 / low density lipoprotein receptor adaptor protein 1
  
Possible biological names infered from orthology : Q5SW96 / Q8C142
  
Species: Gallus gallus
  
Chr. number: 23
Strand: -1
Band:
Gene start: 2349304
Gene end: 2363415
  
Corresponding Affymetrix probe sets: Gga.4014.1.S1_at (Chicken Array)   GgaAffx.690.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000001572
NCBI entrez gene - 419589     See in Manteia.
RefSeq - XM_015297732
swissprot - E1BQU5
Ensembl - ENSGALG00000001051
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ldlrap1aENSDARG00000004311Danio rerio
 ldlrap1bENSDARG00000039750Danio rerio
 Q5SW96ENSG00000157978Homo sapiens
 Q8C142ENSMUSG00000037295Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ENSGALG0000001650838
NUMB / protein numb homolog / NUMBL* / Q9Y6R0* / O08919* / Numb-like protein * / NUMB like, endocytic adaptor protein*ENSGALG0000000930021


Protein motifs (from Interpro)
Interpro ID Name
 IPR006020  PTB/PI domain
 IPR011993  PH-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006898 receptor-mediated endocytosis IEA
 biological_processGO:0009967 positive regulation of signal transduction IEA
 biological_processGO:0031623 receptor internalization IEA
 biological_processGO:0034383 low-density lipoprotein particle clearance IEA
 biological_processGO:0042632 cholesterol homeostasis IEA
 biological_processGO:0042982 amyloid precursor protein metabolic process IEA
 biological_processGO:0043393 regulation of protein binding IEA
 biological_processGO:0048260 positive regulation of receptor-mediated endocytosis IEA
 biological_processGO:0090118 receptor-mediated endocytosis involved in cholesterol transport IEA
 biological_processGO:1903076 regulation of protein localization to plasma membrane IEA
 biological_processGO:1905602 positive regulation of receptor-mediated endocytosis involved in cholesterol transport IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005769 early endosome IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005883 neurofilament IEA
 cellular_componentGO:0009898 cytoplasmic side of plasma membrane IEA
 cellular_componentGO:0009925 basal plasma membrane IEA
 cellular_componentGO:0030121 AP-1 adaptor complex IEA
 cellular_componentGO:0030122 AP-2 adaptor complex IEA
 cellular_componentGO:0055037 recycling endosome IEA
 molecular_functionGO:0001540 amyloid-beta binding IEA
 molecular_functionGO:0001784 phosphotyrosine residue binding IEA
 molecular_functionGO:0005546 phosphatidylinositol-4,5-bisphosphate binding IEA
 molecular_functionGO:0030159 receptor signaling complex scaffold activity IEA
 molecular_functionGO:0030276 clathrin binding IEA
 molecular_functionGO:0035591 signaling adaptor activity IEA
 molecular_functionGO:0035612 AP-2 adaptor complex binding IEA
 molecular_functionGO:0035615 clathrin adaptor activity IEA
 molecular_functionGO:0050750 low-density lipoprotein particle receptor binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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