ENSGALG00000001058


Gallus gallus

Features
Gene ID: ENSGALG00000001058
  
Biological name :ARHGEF16
  
Synonyms : ARHGEF16 / Rho guanine nucleotide exchange factor 16
  
Possible biological names infered from orthology : Q3U5C8 / Q5VV41
  
Species: Gallus gallus
  
Chr. number: 21
Strand: -1
Band:
Gene start: 1013086
Gene end: 1019368
  
Corresponding Affymetrix probe sets: Gga.10015.1.S1_at (Chicken Array)   Gga.15750.1.S1_at (Chicken Array)   Gga.15750.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000001583
NCBI entrez gene - 419386     See in Manteia.
RefSeq - XM_004947371
RefSeq - XM_004947372
RefSeq - XM_417549
swissprot - E1BQT7
Ensembl - ENSGALG00000001058
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 arhgef16ENSDARG00000077114Danio rerio
 Q5VV41ENSG00000130762Homo sapiens
 Q3U5C8ENSMUSG00000029032Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ARHGEF26 / Rho guanine nucleotide exchange factor 26 / Q96DR7* / Rho guanine nucleotide exchange factor (GEF) 26*ENSGALG0000001035248
NGEF / neuronal guanine nucleotide exchange factor / Q8CHT1* / Q8N5V2* / Ephexin-1 *ENSGALG0000003632730
E9Q7D5* / Q12774* / ARHGEF5* / Rho guanine nucleotide exchange factor 5*ENSGALG0000001727627


Protein motifs (from Interpro)
Interpro ID Name
 IPR000219  Dbl homology (DH) domain
 IPR001452  SH3 domain
 IPR001849  Pleckstrin homology domain
 IPR011993  PH-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0035023 regulation of Rho protein signal transduction IEA
 biological_processGO:0060326 cell chemotaxis IEA
 biological_processGO:0090630 activation of GTPase activity IEA
 biological_processGO:1903078 positive regulation of protein localization to plasma membrane IEA
 molecular_functionGO:0005089 Rho guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0017048 Rho GTPase binding IEA
 molecular_functionGO:0030165 PDZ domain binding IEA
 molecular_functionGO:0030971 receptor tyrosine kinase binding IEA
 molecular_functionGO:0045296 cadherin binding IEA


Pathways (from Reactome)
Pathway description
NRAGE signals death through JNK
Rho GTPase cycle
G alpha (12/13) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr