ENSMUSG00000029032


Mus musculus

Features
Gene ID: ENSMUSG00000029032
  
Biological name :Arhgef16
  
Synonyms : Arhgef16 / Q3U5C8 / Rho guanine nucleotide exchange factor 16
  
Possible biological names infered from orthology : Q5VV41
  
Species: Mus musculus
  
Chr. number: 4
Strand: -1
Band: E2
Gene start: 154278486
Gene end: 154301676
  
Corresponding Affymetrix probe sets: 10519012 (MoGene1.0st)   1427386_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000121273
Ensembl peptide - ENSMUSP00000126296
Ensembl peptide - ENSMUSP00000030898
Ensembl peptide - ENSMUSP00000119398
NCBI entrez gene - 230972     See in Manteia.
MGI - MGI:2446219
RefSeq - XM_006538829
RefSeq - XM_011250241
RefSeq - XM_011250242
RefSeq - NM_001112744
RefSeq Peptide - NP_001106215
swissprot - Q3U5C8
swissprot - B1ASH7
swissprot - B1ASH8
Ensembl - ENSMUSG00000029032
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 arhgef16ENSDARG00000077114Danio rerio
 ARHGEF16ENSGALG00000001058Gallus gallus
 Q5VV41ENSG00000130762Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Arhgef26 / Rho guanine nucleotide exchange factor (GEF) 26 / Q96DR7* / Rho guanine nucleotide exchange factor 26*ENSMUSG0000003688545
E9Q7D5 / Arhgef5 / Rho guanine nucleotide exchange factor 5 / Q12774*ENSMUSG0000003354230
Ngef / Q8CHT1 / Ephexin-1 / Q8N5V2* / neuronal guanine nucleotide exchange factor*ENSMUSG0000002625927
Q8BWA8 / Arhgef19 / Rho guanine nucleotide exchange factor 19 / Q8IW93*ENSMUSG0000002891927
Q5FWH6 / Arhgef15 / Rho guanine nucleotide exchange factor 15 / O94989*ENSMUSG0000005292125


Protein motifs (from Interpro)
Interpro ID Name
 IPR000219  Dbl homology (DH) domain
 IPR001452  SH3 domain
 IPR001849  Pleckstrin homology domain
 IPR011993  PH-like domain superfamily
 IPR035797  ARHGEF16/ARHGEF26, SH3 domain
 IPR035899  Dbl homology (DH) domain superfamily
 IPR036028  SH3-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0035023 regulation of Rho protein signal transduction IEA
 biological_processGO:0060326 cell chemotaxis ISS
 biological_processGO:0090630 activation of GTPase activity ISO
 biological_processGO:1903078 positive regulation of protein localization to plasma membrane ISO
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0005085 guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0005089 Rho guanyl-nucleotide exchange factor activity ISS
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0017048 Rho GTPase binding ISO
 molecular_functionGO:0030165 PDZ domain binding ISO
 molecular_functionGO:0030971 receptor tyrosine kinase binding ISO
 molecular_functionGO:0045296 cadherin binding ISO


Pathways (from Reactome)
Pathway description
NRAGE signals death through JNK
Rho GTPase cycle
G alpha (12/13) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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