ENSMUSG00000028919


Mus musculus

Features
Gene ID: ENSMUSG00000028919
  
Biological name :Arhgef19
  
Synonyms : Arhgef19 / Q8BWA8 / Rho guanine nucleotide exchange factor 19
  
Possible biological names infered from orthology : Q8IW93
  
Species: Mus musculus
  
Chr. number: 4
Strand: 1
Band: D3
Gene start: 141239499
Gene end: 141257564
  
Corresponding Affymetrix probe sets: 10509947 (MoGene1.0st)   1437629_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000119846
Ensembl peptide - ENSMUSP00000006618
Ensembl peptide - ENSMUSP00000120088
Ensembl peptide - ENSMUSP00000115856
Ensembl peptide - ENSMUSP00000118740
Ensembl peptide - ENSMUSP00000116274
NCBI entrez gene - 213649     See in Manteia.
MGI - MGI:1925912
RefSeq - XM_017320098
RefSeq - XM_006538704
RefSeq - XM_006538705
RefSeq - XM_006538706
RefSeq - XM_006538707
RefSeq - XM_006538708
RefSeq - XM_006538709
RefSeq - XM_011250225
RefSeq - NM_172520
RefSeq Peptide - NP_766108
swissprot - A2A828
swissprot - A2A827
swissprot - A2A829
swissprot - A2A832
swissprot - Q8BWA8
swissprot - A2A826
Ensembl - ENSMUSG00000028919
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 arhgef19ENSDARG00000078853Danio rerio
 Q8IW93ENSG00000142632Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
E9Q7D5 / Arhgef5 / Rho guanine nucleotide exchange factor 5 / Q12774*ENSMUSG0000003354242
Ngef / Q8CHT1 / Ephexin-1 / Q8N5V2* / neuronal guanine nucleotide exchange factor*ENSMUSG0000002625928
Q5FWH6 / Arhgef15 / Rho guanine nucleotide exchange factor 15 / O94989*ENSMUSG0000005292126
Arhgef26 / Rho guanine nucleotide exchange factor (GEF) 26 / Q96DR7* / Rho guanine nucleotide exchange factor 26*ENSMUSG0000003688525
Q3U5C8 / Arhgef16 / Rho guanine nucleotide exchange factor 16 / Q5VV41*ENSMUSG0000002903224


Protein motifs (from Interpro)
Interpro ID Name
 IPR000219  Dbl homology (DH) domain
 IPR001452  SH3 domain
 IPR001849  Pleckstrin homology domain
 IPR011993  PH-like domain superfamily
 IPR035899  Dbl homology (DH) domain superfamily
 IPR036028  SH3-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0032956 regulation of actin cytoskeleton organization IEA
 biological_processGO:0035023 regulation of Rho protein signal transduction IEA
 biological_processGO:0042060 wound healing IMP
 biological_processGO:0043547 positive regulation of GTPase activity IGI
 molecular_functionGO:0005085 guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0005089 Rho guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0005096 GTPase activator activity IEA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
NRAGE signals death through JNK
Rho GTPase cycle
G alpha (12/13) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr