ENSGALG00000001169


Gallus gallus

Features
Gene ID: ENSGALG00000001169
  
Biological name :CRB2
  
Synonyms : CRB2 / crumbs 2, cell polarity complex component
  
Possible biological names infered from orthology : 2 / Q5IJ48 / Q80YA8
  
Species: Gallus gallus
  
Chr. number: 17
Strand: 1
Band:
Gene start: 9474863
Gene end: 9499855
  
Corresponding Affymetrix probe sets: Gga.11240.1.S1_s_at (Chicken Array)   GgaAffx.23381.1.S1_at (Chicken Array)   GgaAffx.23381.2.S1_at (Chicken Array)   GgaAffx.23381.3.S1_at (Chicken Array)   GgaAffx.23381.3.S1_s_at (Chicken Array)   GgaAffx.23381.4.S1_at (Chicken Array)   GgaAffx.23381.4.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000037962
NCBI entrez gene - 417104     See in Manteia.
RefSeq - XM_004946009
RefSeq - XM_015279573
RefSeq - XM_004946010
RefSeq - XM_004946015
swissprot - E1BYW1
Ensembl - ENSGALG00000001169
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 crb2aENSDARG00000060106Danio rerio
 crb2bENSDARG00000060081Danio rerio
 CRB2ENSG00000148204Homo sapiens
 2 ENSMUSG00000035403Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CRB1 / crumbs 1, cell polarity complex component / 1 * / P82279* / Q8VHS2*ENSGALG0000000228720
SLIT3 / slit guidance ligand 3 / O75094* / Q9WVB4* / Slit homolog 3 protein *ENSGALG0000000191616
SLIT2 / slit homolog 2 protein precursor / O94813* / Q9R1B9* / slit guidance ligand 2*ENSGALG0000004112116
SLIT1 / slit homolog 1 protein precursor / Q80TR4* / O75093* / slit guidance ligand 1* / Slit homolog 1 protein *ENSGALG0000004287115
DNER / delta/notch like EGF repeat containing / Q8JZM4* / Q8NFT8* / Delta and Notch-like epidermal growth factor-related receptor *ENSGALG0000000295812
DLK2 / delta like non-canonical Notch ligand 2 / 2 * / Q6UY11* / Q8K1E3*ENSGALG000000103867
DLK1 / delta like non-canonical Notch ligand 1 / P80370*ENSGALG000000112447


Protein motifs (from Interpro)
Interpro ID Name
 IPR000152  EGF-type aspartate/asparagine hydroxylation site
 IPR000742  EGF-like domain
 IPR001791  Laminin G domain
 IPR001881  EGF-like calcium-binding domain
 IPR009030  Growth factor receptor cysteine-rich domain superfamily
 IPR013032  EGF-like, conserved site
 IPR013320  Concanavalin A-like lectin/glucanase domain superfamily
 IPR018097  EGF-like calcium-binding, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001707 mesoderm formation IEA
 biological_processGO:0001756 somitogenesis IEA
 biological_processGO:0010470 regulation of gastrulation IEA
 biological_processGO:0010718 positive regulation of epithelial to mesenchymal transition IEA
 biological_processGO:0010951 negative regulation of endopeptidase activity IEA
 biological_processGO:0014028 notochord formation IEA
 biological_processGO:0030513 positive regulation of BMP signaling pathway IEA
 biological_processGO:0045199 maintenance of epithelial cell apical/basal polarity IEA
 biological_processGO:0055111 ingression involved in gastrulation with mouth forming second IEA
 biological_processGO:0072358 cardiovascular system development IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016324 apical plasma membrane IEA
 cellular_componentGO:0032991 protein-containing complex IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0019828 aspartic-type endopeptidase inhibitor activity IEA
 molecular_functionGO:0019899 enzyme binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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