ENSGALG00000001250


Gallus gallus

Features
Gene ID: ENSGALG00000001250
  
Biological name :APLP2
  
Synonyms : APLP2
  
Possible biological names infered from orthology : amyloid beta precursor like protein 2 / Amyloid-like protein 2 / Q06335 / Q06481
  
Species: Gallus gallus
  
Chr. number: 24
Strand: -1
Band:
Gene start: 1440224
Gene end: 1481454
  
Corresponding Affymetrix probe sets: Gga.9347.2.S1_s_at (Chicken Array)   Gga.9347.3.S1_a_at (Chicken Array)   GgaAffx.13069.2.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000001896
Ensembl peptide - ENSGALP00000053653
Ensembl peptide - ENSGALP00000001895
NCBI entrez gene - 419727     See in Manteia.
RefSeq - NM_001006317
RefSeq Peptide - NP_001006317
swissprot - A0A1D5PLD7
swissprot - F1P0A7
swissprot - F1P0A9
Ensembl - ENSGALG00000001250
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 aplp2ENSDARG00000054864Danio rerio
 APLP2ENSG00000084234Homo sapiens
 Aplp2ENSMUSG00000031996Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
APP / amyloid beta A4 protein precursor / P05067* / P12023* / amyloid beta precursor protein* / amyloid beta (A4) precursor protein*ENSGALG0000001577052


Protein motifs (from Interpro)
Interpro ID Name
 IPR002223  Pancreatic trypsin inhibitor Kunitz domain
 IPR008154  Amyloidogenic glycoprotein, extracellular
 IPR008155  Amyloidogenic glycoprotein
 IPR011178  Amyloidogenic glycoprotein, copper-binding
 IPR015849  Amyloidogenic glycoprotein, heparin-binding
 IPR019543  Beta-amyloid precursor protein C-terminal
 IPR019744  Amyloidogenic glycoprotein, extracellular domain conserved site
 IPR019745  Amyloidogenic glycoprotein, intracellular domain, conserved site
 IPR020901  Proteinase inhibitor I2, Kunitz, conserved site
 IPR024329  Amyloidogenic glycoprotein, E2 domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010951 negative regulation of endopeptidase activity IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004867 serine-type endopeptidase inhibitor activity IEA
 molecular_functionGO:0008201 heparin binding IEA
 molecular_functionGO:0046914 transition metal ion binding IEA


Pathways (from Reactome)
Pathway description
Platelet degranulation
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Post-translational protein phosphorylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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