ENSGALG00000001610


Gallus gallus

Features
Gene ID: ENSGALG00000001610
  
Biological name :PIP4K2B
  
Synonyms : phosphatidylinositol-5-phosphate 4-kinase type 2 beta / PIP4K2B
  
Possible biological names infered from orthology : P78356 / Q80XI4
  
Species: Gallus gallus
  
Chr. number: 27
Strand: -1
Band:
Gene start: 4437429
Gene end: 4450515
  
Corresponding Affymetrix probe sets: GgaAffx.1053.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000056858
Ensembl peptide - ENSGALP00000002449
NCBI entrez gene - 419999     See in Manteia.
RefSeq - XM_015299519
RefSeq - XM_015299518
swissprot - F1NLK4
swissprot - A0A1D5PV96
Ensembl - ENSGALG00000001610
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 P78356ENSG00000276293Homo sapiens
 Q80XI4ENSMUSG00000018547Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PIP4K2A / phosphatidylinositol 5-phosphate 4-kinase type-2 alpha / O70172* / P48426*ENSGALG0000000787776
PIP5K1A / phosphatidylinositol 4-phosphate 5-kinase type-1 alpha / P70182* / Q99755*ENSGALG0000002737231
PIP5K1C / Gallus gallus phosphatidylinositol-4-phosphate 5-kinase, type I, gamma (PIP5K1C), mRNA. / O60331* / O70161* / phosphatidylinositol-4-phosphate 5-kinase type 1 gamma*ENSGALG0000000078430
PIP5K1B / phosphatidylinositol 4-phosphate 5-kinase type-1 beta / O14986* / P70181*ENSGALG0000001510729


Protein motifs (from Interpro)
Interpro ID Name
 IPR002498  Phosphatidylinositol-4-phosphate 5-kinase, core
 IPR023610  Phosphatidylinositol-4-phosphate 5-kinase
 IPR027483  Phosphatidylinositol-4-phosphate 5-kinase, C-terminal
 IPR027484  Phosphatidylinositol-4-phosphate 5-kinase, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010506 regulation of autophagy IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0046488 phosphatidylinositol metabolic process IEA
 biological_processGO:0046854 phosphatidylinositol phosphorylation IEA
 biological_processGO:2000786 positive regulation of autophagosome assembly IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005776 autophagosome IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016307 phosphatidylinositol phosphate kinase activity IEA
 molecular_functionGO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA


Pathways (from Reactome)
Pathway description
Synthesis of PIPs at the plasma membrane
PI5P Regulates TP53 Acetylation
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
Synthesis of PIPs in the nucleus


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000001610 PIP4K2B / phosphatidylinositol-5-phosphate 4-kinase type 2 beta / P78356* / Q80XI4*  / complex
 ENSGALG00000004370 MAP2K6 / mitogen-activated protein kinase kinase 6 / P52564* / P70236*  / reaction






 

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