ENSGALG00000001876


Gallus gallus

Features
Gene ID: ENSGALG00000001876
  
Biological name :RASA4
  
Synonyms : RASA4
  
Possible biological names infered from orthology : C9J798 / O43374 / Q6PFQ7 / RASA4B / RAS p21 protein activator 4 / RAS p21 protein activator 4B
  
Species: Gallus gallus
  
Chr. number: 19
Strand: -1
Band:
Gene start: 4142037
Gene end: 4148992
  
Corresponding Affymetrix probe sets: Gga.19155.1.S1_at (Chicken Array)   GgaAffx.1233.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000002907
NCBI entrez gene - 417513     See in Manteia.
RefSeq - NM_001291781
RefSeq - XM_015295710
RefSeq - XM_015295711
RefSeq Peptide - NP_001278710
swissprot - F1NF56
Ensembl - ENSGALG00000001876
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rasa4ENSDARG00000029372Danio rerio
 C9J798ENSG00000170667Homo sapiens
 RASA4ENSG00000105808Homo sapiens
 Rasa4ENSMUSG00000004952Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RASAL1 / RAS protein activator like 1 / O95294* / Q9Z268* / Mus musculus RAS protein activator like 1 (GAP1 like) (Rasal1), transcript variant 3, mRNA.*ENSGALG0000000815046
RASA3 / RAS p21 protein activator 3 / Q14644* / Q60790* / Ras GTPase-activating protein 3 *ENSGALG0000001681730
RASA2 / RAS p21 protein activator 2 / P58069* / Q15283* / Ras GTPase-activating protein 2 *ENSGALG0000000285028
DAB2IP / DAB2 interacting protein / Q3UHC7* / Q5VWQ8* / Disabled homolog 2-interacting protein *ENSGALG0000000141920
RASAL2 / RAS protein activator like 2 / Q9UJF2*ENSGALG0000000432320
RASA1* / P20936* / RAS p21 protein activator 1*ENSGALG0000001770616
ENSGALG000000368861


Protein motifs (from Interpro)
Interpro ID Name
 IPR000008  C2 domain
 IPR001562  Zinc finger, Btk motif
 IPR001849  Pleckstrin homology domain
 IPR001936  Ras GTPase-activating domain
 IPR008936  Rho GTPase activation protein
 IPR011993  PH-like domain superfamily
 IPR023152  Ras GTPase-activating protein, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0043087 regulation of GTPase activity IEA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0046580 negative regulation of Ras protein signal transduction IBA
 biological_processGO:0071277 cellular response to calcium ion IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane IBA
 molecular_functionGO:0005096 GTPase activator activity IBA
 molecular_functionGO:0005543 phospholipid binding IEA


Pathways (from Reactome)
Pathway description
Regulation of RAS by GAPs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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