ENSDARG00000029372


Danio rerio

Features
Gene ID: ENSDARG00000029372
  
Biological name :rasa4
  
Synonyms : rasa4 / RAS p21 protein activator 4
  
Possible biological names infered from orthology : C9J798 / O43374 / Q6PFQ7 / RASA4B / RAS p21 protein activator 4B
  
Species: Danio rerio
  
Chr. number: 5
Strand: 1
Band:
Gene start: 59278193
Gene end: 59391081
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000088144
Ensembl peptide - ENSDARP00000131397
NCBI entrez gene - 567599     See in Manteia.
RefSeq - NM_001099451
RefSeq Peptide - NP_001092921
swissprot - A2CE77
swissprot - A0A0R4IE78
ZFIN ID - ZDB-GENE-060526-349
Ensembl - ENSDARG00000029372
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 RASA4ENSGALG00000001876Gallus gallus
 C9J798ENSG00000170667Homo sapiens
 RASA4ENSG00000105808Homo sapiens
 Rasa4ENSMUSG00000004952Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
rasa3 / RAS p21 protein activator 3 / Q14644* / Q60790* / Ras GTPase-activating protein 3 *ENSDARG0000006337130
CABZ01005876.1 / RASA2* / Q15283* / RAS p21 protein activator 2*ENSDARG0000007877526
syngap1a / synaptic Ras GTPase activating protein 1a / Q96PV0* / F6SEU4* / SYNGAP1* / synaptic Ras GTPase activating protein 1* / Ras/Rap GTPase-activating protein SynGAP *ENSDARG0000006371320
dab2ipa / DAB2 interacting protein a / Q3UHC7* / DAB2IP* / Q5VWQ8* / DAB2 interacting protein* / Disabled homolog 2-interacting protein *ENSDARG0000006948420
dab2ipb / DAB2 interacting protein bENSDARG0000007511020
rasal2 / RAS protein activator like 2 / Q9UJF2*ENSDARG0000003625719
syngap1b / synaptic Ras GTPase activating protein 1b / Q96PV0* / F6SEU4* / SYNGAP1* / synaptic Ras GTPase activating protein 1* / Ras/Rap GTPase-activating protein SynGAP *ENSDARG0000006976519
rasal1b / RAS protein activator like 1b (GAP1 like) / Q9Z268* / RASAL1* / O95294* / RAS protein activator like 1* / Mus musculus RAS protein activator like 1 (GAP1 like) (Rasal1), transcrip...ENSDARG0000004151517
rasal3 / RAS protein activator like 3 / Q86YV0* / Q8C2K5*ENSDARG0000008993316
rasa1a / RAS p21 protein activator (GTPase activating protein) 1a / RASA1* / P20936* / RAS p21 protein activator 1*ENSDARG0000003553515
rasa1b / RAS p21 protein activator (GTPase activating protein) 1b / RASA1* / P20936* / RAS p21 protein activator 1*ENSDARG0000007366514


Protein motifs (from Interpro)
Interpro ID Name
 IPR000008  C2 domain
 IPR001562  Zinc finger, Btk motif
 IPR001849  Pleckstrin homology domain
 IPR001936  Ras GTPase-activating domain
 IPR008936  Rho GTPase activation protein
 IPR011993  PH-like domain superfamily
 IPR023152  Ras GTPase-activating protein, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0043087 regulation of GTPase activity IEA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0046580 negative regulation of Ras protein signal transduction IEA
 biological_processGO:0071277 cellular response to calcium ion IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane IBA
 molecular_functionGO:0005096 GTPase activator activity IEA
 molecular_functionGO:0005543 phospholipid binding IEA


Pathways (from Reactome)
Pathway description
Regulation of RAS by GAPs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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