ENSDARG00000063371


Danio rerio

Features
Gene ID: ENSDARG00000063371
  
Biological name :rasa3
  
Synonyms : rasa3 / RAS p21 protein activator 3
  
Possible biological names infered from orthology : Q14644 / Q60790 / Ras GTPase-activating protein 3
  
Species: Danio rerio
  
Chr. number: 1
Strand: -1
Band:
Gene start: 357518
Gene end: 411331
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000086956
NCBI entrez gene - 100318936     See in Manteia.
swissprot - E7F916
ZFIN ID - ZDB-GENE-090313-21
Ensembl - ENSDARG00000063371
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 RASA3ENSGALG00000016817Gallus gallus
 RASA3ENSG00000185989Homo sapiens
 Rasa3ENSMUSG00000031453Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CABZ01005876.1 / RASA2* / Q15283* / RAS p21 protein activator 2*ENSDARG0000007877551
rasa4 / RAS p21 protein activator 4 / RASA4B* / C9J798* / O43374* / Q6PFQ7* / RAS p21 protein activator 4B*ENSDARG0000002937229
syngap1b / synaptic Ras GTPase activating protein 1b / Q96PV0* / F6SEU4* / SYNGAP1* / synaptic Ras GTPase activating protein 1* / Ras/Rap GTPase-activating protein SynGAP *ENSDARG0000006976519
syngap1a / synaptic Ras GTPase activating protein 1a / Q96PV0* / F6SEU4* / SYNGAP1* / synaptic Ras GTPase activating protein 1* / Ras/Rap GTPase-activating protein SynGAP *ENSDARG0000006371319
dab2ipb / DAB2 interacting protein bENSDARG0000007511019
dab2ipa / DAB2 interacting protein a / Q3UHC7* / DAB2IP* / Q5VWQ8* / DAB2 interacting protein* / Disabled homolog 2-interacting protein *ENSDARG0000006948419
rasal2 / RAS protein activator like 2 / Q9UJF2*ENSDARG0000003625718
rasal3 / RAS protein activator like 3 / Q86YV0* / Q8C2K5*ENSDARG0000008993315
rasa1a / RAS p21 protein activator (GTPase activating protein) 1a / RASA1* / P20936* / RAS p21 protein activator 1*ENSDARG0000003553515
rasa1b / RAS p21 protein activator (GTPase activating protein) 1b / RASA1* / P20936* / RAS p21 protein activator 1*ENSDARG0000007366514
rasal1b / RAS protein activator like 1b (GAP1 like) / Q9Z268* / RASAL1* / O95294* / RAS protein activator like 1* / Mus musculus RAS protein activator like 1 (GAP1 like) (Rasal1), transcrip...ENSDARG0000004151510


Protein motifs (from Interpro)
Interpro ID Name
 IPR000008  C2 domain
 IPR001562  Zinc finger, Btk motif
 IPR001849  Pleckstrin homology domain
 IPR001936  Ras GTPase-activating domain
 IPR008936  Rho GTPase activation protein
 IPR011993  PH-like domain superfamily
 IPR023152  Ras GTPase-activating protein, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002574 thrombocyte differentiation IMP
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0043087 regulation of GTPase activity IEA
 biological_processGO:0043363 nucleate erythrocyte differentiation IMP
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0046580 negative regulation of Ras protein signal transduction IBA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane IBA
 molecular_functionGO:0005096 GTPase activator activity IBA


Pathways (from Reactome)
Pathway description
Regulation of RAS by GAPs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0009256 nucleate erythrocyte nucleate erythrocyte hemoglobin complex decreased amount , abnormal
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 ZFA:0009323 thrombocyte thrombocyte decreased amount , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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