ENSDARG00000036257


Danio rerio

Features
Gene ID: ENSDARG00000036257
  
Biological name :rasal2
  
Synonyms : rasal2 / RAS protein activator like 2
  
Possible biological names infered from orthology : Q9UJF2
  
Species: Danio rerio
  
Chr. number: 2
Strand: 1
Band:
Gene start: 35732652
Gene end: 35851661
  
Corresponding Affymetrix probe sets: Dr.12562.1.A1_at (Zebrafish Array)   Dr.24417.1.A1_at (Zebrafish Array)   XM_001332652_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000052665
Ensembl peptide - ENSDARP00000117093
Ensembl peptide - ENSDARP00000102916
NCBI entrez gene - 793730     See in Manteia.
RefSeq - XM_001332652
swissprot - B0S6Z2
swissprot - B0S6Z0
swissprot - F1QX32
ZFIN ID - ZDB-GENE-070912-180
Ensembl - ENSDARG00000036257
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 RASAL2ENSGALG00000004323Gallus gallus
 Q9UJF2ENSG00000075391Homo sapiens
 Rasal2ENSMUSG00000070565Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
dab2ipb / DAB2 interacting protein bENSDARG0000007511050
dab2ipa / DAB2 interacting protein a / Q3UHC7* / DAB2IP* / Q5VWQ8* / DAB2 interacting protein* / Disabled homolog 2-interacting protein *ENSDARG0000006948450
syngap1b / synaptic Ras GTPase activating protein 1b / Q96PV0* / F6SEU4* / SYNGAP1* / synaptic Ras GTPase activating protein 1* / Ras/Rap GTPase-activating protein SynGAP *ENSDARG0000006976542
syngap1a / synaptic Ras GTPase activating protein 1a / Q96PV0* / F6SEU4* / SYNGAP1* / synaptic Ras GTPase activating protein 1* / Ras/Rap GTPase-activating protein SynGAP *ENSDARG0000006371340
rasal3 / RAS protein activator like 3 / Q86YV0* / Q8C2K5*ENSDARG0000008993327
rasa1b / RAS p21 protein activator (GTPase activating protein) 1b / RASA1* / P20936* / RAS p21 protein activator 1*ENSDARG0000007366514
rasa1a / RAS p21 protein activator (GTPase activating protein) 1a / RASA1* / P20936* / RAS p21 protein activator 1*ENSDARG0000003553514
rasa4 / RAS p21 protein activator 4 / RASA4B* / C9J798* / O43374* / Q6PFQ7* / RAS p21 protein activator 4B*ENSDARG0000002937212
rasa3 / RAS p21 protein activator 3 / Q14644* / Q60790* / Ras GTPase-activating protein 3 *ENSDARG0000006337111
CABZ01005876.1 / RASA2* / Q15283* / RAS p21 protein activator 2*ENSDARG0000007877510
rasal1b / RAS protein activator like 1b (GAP1 like) / Q9Z268* / RASAL1* / O95294* / RAS protein activator like 1* / Mus musculus RAS protein activator like 1 (GAP1 like) (Rasal1), transcrip...ENSDARG000000415153


Protein motifs (from Interpro)
Interpro ID Name
 IPR000008  C2 domain
 IPR001849  Pleckstrin homology domain
 IPR001936  Ras GTPase-activating domain
 IPR008936  Rho GTPase activation protein
 IPR011993  PH-like domain superfamily
 IPR021887  Domain of unknown function DUF3498
 IPR023152  Ras GTPase-activating protein, conserved site
 IPR023315  SynGAP C2 domain, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0043087 regulation of GTPase activity IEA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0046580 negative regulation of Ras protein signal transduction IBA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane IBA
 molecular_functionGO:0005096 GTPase activator activity IBA


Pathways (from Reactome)
Pathway description
Regulation of RAS by GAPs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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