ENSDARG00000069484


Danio rerio

Features
Gene ID: ENSDARG00000069484
  
Biological name :dab2ipa
  
Synonyms : DAB2 interacting protein a / dab2ipa
  
Possible biological names infered from orthology : DAB2 interacting protein / DAB2IP / Disabled homolog 2-interacting protein / Q3UHC7 / Q5VWQ8
  
Species: Danio rerio
  
Chr. number: 8
Strand: -1
Band:
Gene start: 12134127
Gene end: 12264521
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000086045
Ensembl peptide - ENSDARP00000115386
swissprot - F1Q588
swissprot - F1Q782
ZFIN ID - ZDB-GENE-081104-516
Ensembl - ENSDARG00000069484
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 DAB2IPENSGALG00000001419Gallus gallus
 DAB2IPENSG00000136848Homo sapiens
 Dab2ipENSMUSG00000026883Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
dab2ipb / DAB2 interacting protein bENSDARG0000007511077
rasal2 / RAS protein activator like 2 / Q9UJF2*ENSDARG0000003625758
syngap1b / synaptic Ras GTPase activating protein 1b / Q96PV0* / F6SEU4* / SYNGAP1* / synaptic Ras GTPase activating protein 1* / Ras/Rap GTPase-activating protein SynGAP *ENSDARG0000006976550
syngap1a / synaptic Ras GTPase activating protein 1a / Q96PV0* / F6SEU4* / SYNGAP1* / synaptic Ras GTPase activating protein 1* / Ras/Rap GTPase-activating protein SynGAP *ENSDARG0000006371349
rasal3 / RAS protein activator like 3 / Q86YV0* / Q8C2K5*ENSDARG0000008993332
rasa1a / RAS p21 protein activator (GTPase activating protein) 1a / RASA1* / P20936* / RAS p21 protein activator 1*ENSDARG0000003553515
rasa1b / RAS p21 protein activator (GTPase activating protein) 1b / RASA1* / P20936* / RAS p21 protein activator 1*ENSDARG0000007366515
rasa4 / RAS p21 protein activator 4 / RASA4B* / C9J798* / O43374* / Q6PFQ7* / RAS p21 protein activator 4B*ENSDARG0000002937214
rasa3 / RAS p21 protein activator 3 / Q14644* / Q60790* / Ras GTPase-activating protein 3 *ENSDARG0000006337114
CABZ01005876.1 / RASA2* / Q15283* / RAS p21 protein activator 2*ENSDARG0000007877512
rasal1b / RAS protein activator like 1b (GAP1 like) / Q9Z268* / RASAL1* / O95294* / RAS protein activator like 1* / Mus musculus RAS protein activator like 1 (GAP1 like) (Rasal1), transcrip...ENSDARG000000415154


Protein motifs (from Interpro)
Interpro ID Name
 IPR000008  C2 domain
 IPR001849  Pleckstrin homology domain
 IPR001936  Ras GTPase-activating domain
 IPR008936  Rho GTPase activation protein
 IPR011993  PH-like domain superfamily
 IPR021887  Domain of unknown function DUF3498
 IPR023152  Ras GTPase-activating protein, conserved site
 IPR023315  SynGAP C2 domain, N-terminal
 IPR030403  Disabled homologue 2-interacting protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0008285 negative regulation of cell proliferation IEA
 biological_processGO:0016525 negative regulation of angiogenesis IEA
 biological_processGO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway IEA
 biological_processGO:0038026 reelin-mediated signaling pathway IEA
 biological_processGO:0043065 positive regulation of apoptotic process IEA
 biological_processGO:0043087 regulation of GTPase activity IEA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0046580 negative regulation of Ras protein signal transduction IBA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane IBA
 molecular_functionGO:0005096 GTPase activator activity IBA


Pathways (from Reactome)
Pathway description
Regulation of RAS by GAPs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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