ENSDARG00000063713


Danio rerio

Features
Gene ID: ENSDARG00000063713
  
Biological name :syngap1a
  
Synonyms : synaptic Ras GTPase activating protein 1a / syngap1a
  
Possible biological names infered from orthology : F6SEU4 / Q96PV0 / Ras/Rap GTPase-activating protein SynGAP / synaptic Ras GTPase activating protein 1 / SYNGAP1
  
Species: Danio rerio
  
Chr. number: 19
Strand: 1
Band:
Gene start: 232536
Gene end: 276802
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000117619
Ensembl peptide - ENSDARP00000144044
swissprot - A0A286YAN7
swissprot - E9QBX6
swissprot - F1QY93
ZFIN ID - ZDB-GENE-060503-370
Ensembl - ENSDARG00000063713
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q96PV0ENSG00000197283Homo sapiens
 F6SEU4ENSMUSG00000067629Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
syngap1b / synaptic Ras GTPase activating protein 1b / Q96PV0* / F6SEU4* / SYNGAP1* / synaptic Ras GTPase activating protein 1* / Ras/Rap GTPase-activating protein SynGAP *ENSDARG0000006976577
dab2ipa / DAB2 interacting protein a / Q3UHC7* / DAB2IP* / Q5VWQ8* / DAB2 interacting protein* / Disabled homolog 2-interacting protein *ENSDARG0000006948443
dab2ipb / DAB2 interacting protein bENSDARG0000007511043
rasal2 / RAS protein activator like 2 / Q9UJF2*ENSDARG0000003625742
rasal3 / RAS protein activator like 3 / Q86YV0* / Q8C2K5*ENSDARG0000008993326
rasa1a / RAS p21 protein activator (GTPase activating protein) 1a / RASA1* / P20936* / RAS p21 protein activator 1*ENSDARG0000003553513
rasa1b / RAS p21 protein activator (GTPase activating protein) 1b / RASA1* / P20936* / RAS p21 protein activator 1*ENSDARG0000007366513
rasa4 / RAS p21 protein activator 4 / RASA4B* / C9J798* / O43374* / Q6PFQ7* / RAS p21 protein activator 4B*ENSDARG0000002937212
rasa3 / RAS p21 protein activator 3 / Q14644* / Q60790* / Ras GTPase-activating protein 3 *ENSDARG0000006337112
CABZ01005876.1 / RASA2* / Q15283* / RAS p21 protein activator 2*ENSDARG0000007877511
rasal1b / RAS protein activator like 1b (GAP1 like) / Q9Z268* / RASAL1* / O95294* / RAS protein activator like 1* / Mus musculus RAS protein activator like 1 (GAP1 like) (Rasal1), transcrip...ENSDARG000000415154


Protein motifs (from Interpro)
Interpro ID Name
 IPR000008  C2 domain
 IPR001849  Pleckstrin homology domain
 IPR001936  Ras GTPase-activating domain
 IPR008936  Rho GTPase activation protein
 IPR011993  PH-like domain superfamily
 IPR021887  Domain of unknown function DUF3498
 IPR023152  Ras GTPase-activating protein, conserved site
 IPR023315  SynGAP C2 domain, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0043087 regulation of GTPase activity IEA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0046580 negative regulation of Ras protein signal transduction IBA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane IBA
 molecular_functionGO:0005096 GTPase activator activity IBA


Pathways (from Reactome)
Pathway description
Regulation of RAS by GAPs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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