ENSG00000170667


Homo sapiens

Features
Gene ID: ENSG00000170667
  
Biological name :RASA4B
  
Synonyms : C9J798 / RASA4B / RAS p21 protein activator 4B
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: -1
Band: q22.1
Gene start: 102482445
Gene end: 102517781
  
Corresponding Affymetrix probe sets: 208534_s_at (Human Genome U133 Plus 2.0 Array)   212707_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000440982
Ensembl peptide - ENSP00000303968
Ensembl peptide - ENSP00000417895
NCBI entrez gene - 100271927     See in Manteia.
RefSeq - XM_017011627
RefSeq - NM_001277335
RefSeq - XM_005250084
RefSeq - XM_011515690
RefSeq - XM_017011626
RefSeq Peptide - NP_001264264
swissprot - F5GXT2
swissprot - F8W6L0
swissprot - C9J798
Ensembl - ENSG00000170667
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rasa4ENSDARG00000029372Danio rerio
 RASA4ENSGALG00000001876Gallus gallus
 Rasa4ENSMUSG00000004952Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RASA4 / O43374 / RAS p21 protein activator 4ENSG00000105808100
O95294 / RASAL1 / RAS protein activator like 1ENSG0000011134449
RASA3 / Q14644 / RAS p21 protein activator 3ENSG0000018598931
RASA2 / Q15283 / RAS p21 protein activator 2ENSG0000015590330
Q9UJF2 / RASAL2 / RAS protein activator like 2ENSG0000007539122
Q96PV0 / SYNGAP1 / synaptic Ras GTPase activating protein 1ENSG0000019728321
DAB2IP / Q5VWQ8 / DAB2 interacting proteinENSG0000013684821
Q86YV0 / RASAL3 / RAS protein activator like 3ENSG0000010512218
RASA1 / P20936 / RAS p21 protein activator 1ENSG0000014571516


Protein motifs (from Interpro)
Interpro ID Name
 IPR000008  C2 domain
 IPR001562  Zinc finger, Btk motif
 IPR001849  Pleckstrin homology domain
 IPR001936  Ras GTPase-activating domain
 IPR008936  Rho GTPase activation protein
 IPR011993  PH-like domain superfamily
 IPR023152  Ras GTPase-activating protein, conserved site
 IPR035892  C2 domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0043087 regulation of GTPase activity IEA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0046580 negative regulation of Ras protein signal transduction IEA
 biological_processGO:0071277 cellular response to calcium ion IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane IBA
 molecular_functionGO:0005096 GTPase activator activity IEA
 molecular_functionGO:0005543 phospholipid binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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