ENSGALG00000002288


Gallus gallus

Features
Gene ID: ENSGALG00000002288
  
Biological name :LIG3
  
Synonyms : DNA ligase 3 / LIG3
  
Possible biological names infered from orthology : ligase III, DNA, ATP-dependent / P49916
  
Species: Gallus gallus
  
Chr. number: 19
Strand: -1
Band:
Gene start: 4477145
Gene end: 4492384
  
Corresponding Affymetrix probe sets: Gga.12748.1.S1_at (Chicken Array)   GgaAffx.11721.1.S1_s_at (Chicken Array)   GgaAffx.21030.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000003592
Ensembl peptide - ENSGALP00000064108
Ensembl peptide - ENSGALP00000046065
NCBI entrez gene - 417530     See in Manteia.
RefSeq - NM_001006215
RefSeq - XM_015295726
RefSeq Peptide - NP_001006215
swissprot - A0A1L1RZ14
swissprot - A0A1D5P091
swissprot - F1P394
Ensembl - ENSGALG00000002288
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 lig3ENSDARG00000052553Danio rerio
 LIG3ENSG00000005156Homo sapiens
 Lig3ENSMUSG00000020697Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000977  DNA ligase, ATP-dependent
 IPR001357  BRCT domain
 IPR001510  Zinc finger, PARP-type
 IPR012308  DNA ligase, ATP-dependent, N-terminal
 IPR012309  DNA ligase, ATP-dependent, C-terminal
 IPR012310  DNA ligase, ATP-dependent, central
 IPR012340  Nucleic acid-binding, OB-fold
 IPR016059  DNA ligase, ATP-dependent, conserved site
 IPR031916  DNA ligase 3, BRCT domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006260 DNA replication IEA
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006288 base-excision repair, DNA ligation IEA
 biological_processGO:0006302 double-strand break repair IEA
 biological_processGO:0006310 DNA recombination IEA
 biological_processGO:0006974 cellular response to DNA damage stimulus IEA
 biological_processGO:0051103 DNA ligation involved in DNA repair IEA
 biological_processGO:0071897 DNA biosynthetic process IEA
 biological_processGO:0090298 negative regulation of mitochondrial DNA replication IEA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005739 mitochondrion IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003909 DNA ligase activity IEA
 molecular_functionGO:0003910 DNA ligase (ATP) activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016874 ligase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000017211 MRE11 / double-strand break repair protein MRE11 / Mre11a* / Q61216* / P49959* / MRE11 homolog, double strand break repair nuclease*  / complex
 ENSGALG00000006794 RAD50* / Q92878* / AC116366.3* / RAD50 double strand break repair protein*  / complex
 ENSGALG00000014982 RBBP8 / RB binding protein 8, endonuclease / Q80YR6* / Q99708* / retinoblastoma binding protein 8, endonuclease*  / complex






 

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