ENSGALG00000002707


Gallus gallus

Features
Gene ID: ENSGALG00000002707
  
Biological name :CHRNB2
  
Synonyms : CHRNB2 / neuronal acetylcholine receptor subunit beta-2 precursor
  
Possible biological names infered from orthology : cholinergic receptor nicotinic beta 2 subunit / cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal) / P17787 / Q9ERK7
  
Species: Gallus gallus
  
Chr. number: 25
Strand: 1
Band:
Gene start: 1729683
Gene end: 1734477
  
Corresponding Affymetrix probe sets: Gga.336.1.S1_at (Chicken Array)   GgaAffx.1768.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000004261
NCBI entrez gene - 395605     See in Manteia.
RefSeq - NM_204813
RefSeq Peptide - NP_990144
swissprot - H9KZ38
Ensembl - ENSGALG00000002707
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 chrnb2bENSDARG00000017790Danio rerio
 CHRNB2ENSG00000160716Homo sapiens
 Chrnb2ENSMUSG00000027950Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CHRNB4 / neuronal acetylcholine receptor subunit beta-4 precursor / P30926* / Q8R493* / cholinergic receptor nicotinic beta 4 subunit* / cholinergic receptor, nicotinic, beta polypeptide 4*ENSGALG0000000300566
CHRNA4 / neuronal acetylcholine receptor subunit alpha-4 precursor / O70174* / P43681* / cholinergic receptor nicotinic alpha 4 subunit* / cholinergic receptor, nicotinic, alpha polypeptide 4*ENSGALG0000000580149
CHRNA2 / neuronal acetylcholine receptor subunit alpha-2 precursor / Q15822* / Q91X60* / cholinergic receptor nicotinic alpha 2 subunit* / cholinergic receptor, nicotinic, alpha polypeptid...ENSGALG0000001656548
CHRNA3 / P09481 / Neuronal acetylcholine receptor subunit alpha-3 / P32297* / cholinergic receptor nicotinic alpha 3 subunit* / cholinergic receptor, nicotinic, alpha polypeptide 3*ENSGALG0000000301444
CHRNA6 / neuronal acetylcholine receptor subunit alpha-6 precursor / Q15825* / Q9R0W9* / cholinergic receptor nicotinic alpha 6 subunit* / cholinergic receptor, nicotinic, alpha polypeptide 6*ENSGALG0000001538243
CHRNA1 / acetylcholine receptor subunit alpha precursor / P02708* / P04756* / cholinergic receptor nicotinic alpha 1 subunit* / cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle)*ENSGALG0000000930140
CHRNA5 / neuronal acetylcholine receptor subunit alpha-5 precursor / P30532* / Q2MKA5* / cholinergic receptor nicotinic alpha 5 subunit* / cholinergic receptor, nicotinic, alpha polypeptide 5*ENSGALG0000000302138
CHRNB3 / cholinergic receptor nicotinic beta 3 subunit / Q05901* / Q8BMN3* / cholinergic receptor, nicotinic, beta polypeptide 3*ENSGALG0000001538437


Protein motifs (from Interpro)
Interpro ID Name
 IPR002394  Nicotinic acetylcholine receptor
 IPR006029  Neurotransmitter-gated ion-channel transmembrane domain
 IPR006201  Neurotransmitter-gated ion-channel
 IPR006202  Neurotransmitter-gated ion-channel ligand-binding domain
 IPR018000  Neurotransmitter-gated ion-channel, conserved site
 IPR032932  Neuronal acetylcholine receptor subunit beta-2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001508 action potential IEA
 biological_processGO:0001661 conditioned taste aversion IEA
 biological_processGO:0001666 response to hypoxia IEA
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006816 calcium ion transport IEA
 biological_processGO:0006939 smooth muscle contraction IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007601 visual perception IEA
 biological_processGO:0007605 sensory perception of sound IEA
 biological_processGO:0007612 learning IEA
 biological_processGO:0007613 memory IEA
 biological_processGO:0007626 locomotory behavior IEA
 biological_processGO:0008306 associative learning IEA
 biological_processGO:0008542 visual learning IEA
 biological_processGO:0014059 regulation of dopamine secretion IEA
 biological_processGO:0019233 sensory perception of pain IEA
 biological_processGO:0021562 vestibulocochlear nerve development IEA
 biological_processGO:0021631 optic nerve morphogenesis IEA
 biological_processGO:0021771 lateral geniculate nucleus development IEA
 biological_processGO:0021952 central nervous system projection neuron axonogenesis IEA
 biological_processGO:0021955 central nervous system neuron axonogenesis IEA
 biological_processGO:0030890 positive regulation of B cell proliferation IEA
 biological_processGO:0032225 regulation of synaptic transmission, dopaminergic IEA
 biological_processGO:0032226 positive regulation of synaptic transmission, dopaminergic IEA
 biological_processGO:0033603 positive regulation of dopamine secretion IEA
 biological_processGO:0034220 ion transmembrane transport IEA
 biological_processGO:0035094 response to nicotine IEA
 biological_processGO:0035095 behavioral response to nicotine IEA
 biological_processGO:0035176 social behavior IEA
 biological_processGO:0042053 regulation of dopamine metabolic process IEA
 biological_processGO:0042113 B cell activation IEA
 biological_processGO:0042220 response to cocaine IEA
 biological_processGO:0042320 regulation of circadian sleep/wake cycle, REM sleep IEA
 biological_processGO:0042391 regulation of membrane potential IEA
 biological_processGO:0045188 regulation of circadian sleep/wake cycle, non-REM sleep IEA
 biological_processGO:0045471 response to ethanol IEA
 biological_processGO:0045759 negative regulation of action potential IEA
 biological_processGO:0048814 regulation of dendrite morphogenesis IEA
 biological_processGO:0050877 nervous system process IEA
 biological_processGO:0050890 cognition IEA
 biological_processGO:0051899 membrane depolarization IEA
 biological_processGO:0051963 regulation of synapse assembly IEA
 biological_processGO:0060078 regulation of postsynaptic membrane potential IEA
 biological_processGO:0060079 excitatory postsynaptic potential IEA
 biological_processGO:0060084 synaptic transmission involved in micturition IEA
 biological_processGO:0095500 acetylcholine receptor signaling pathway IEA
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005892 acetylcholine-gated channel complex IEA
 cellular_componentGO:0009897 external side of plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030424 axon ISS
 cellular_componentGO:0030425 dendrite ISS
 cellular_componentGO:0043204 perikaryon ISS
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0045211 postsynaptic membrane IEA
 molecular_functionGO:0004888 transmembrane signaling receptor activity IEA
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005230 extracellular ligand-gated ion channel activity IEA
 molecular_functionGO:0015464 acetylcholine receptor activity IEA
 molecular_functionGO:0022848 acetylcholine-gated cation-selective channel activity IEA
 molecular_functionGO:0042166 acetylcholine binding IEA


Pathways (from Reactome)
Pathway description
Highly sodium permeable acetylcholine nicotinic receptors
Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
Highly calcium permeable nicotinic acetylcholine receptors


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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