ENSDARG00000017790


Danio rerio

Features
Gene ID: ENSDARG00000017790
  
Biological name :chrnb2b
  
Synonyms : cholinergic receptor, nicotinic, beta 2b / chrnb2b
  
Possible biological names infered from orthology : cholinergic receptor nicotinic beta 2 subunit / cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal) / CHRNB2 / P17787 / Q9ERK7
  
Species: Danio rerio
  
Chr. number: 16
Strand: 1
Band:
Gene start: 22618620
Gene end: 22678294
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000117777
Ensembl peptide - ENSDARP00000151420
Ensembl peptide - ENSDARP00000147304
Ensembl peptide - ENSDARP00000041624
NCBI entrez gene - 561906     See in Manteia.
swissprot - E9QCW8
swissprot - E7F4S7
ZFIN ID - ZDB-GENE-070821-3
Ensembl - ENSDARG00000017790
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CHRNB2ENSGALG00000002707Gallus gallus
 CHRNB2ENSG00000160716Homo sapiens
 Chrnb2ENSMUSG00000027950Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
chrnb4 / cholinergic receptor, nicotinic, beta 4 (neuronal) / P30926* / Q8R493* / cholinergic receptor nicotinic beta 4 subunit* / cholinergic receptor, nicotinic, beta polypeptide 4*ENSDARG0000010167761
chrnb2a / cholinergic receptor, nicotinic, beta 2aENSDARG0000011577859
chrnb2l / cholinergic receptor, nicotinic, beta 2, likeENSDARG0000002139255
chrna2a / cholinergic receptor, nicotinic, alpha 2a (neuronal) / CHRNA2* / Q15822* / Q91X60* / cholinergic receptor nicotinic alpha 2 subunit* / cholinergic receptor, nicotinic, alpha polyp...ENSDARG0000000660243
chrna2b / cholinergic receptor, nicotinic, alpha 2b (neuronal) / CHRNA2* / Q15822* / Q91X60* / cholinergic receptor nicotinic alpha 2 subunit* / cholinergic receptor, nicotinic, alpha polyp...ENSDARG0000005702543
chrna4b / cholinergic receptor, nicotinic, alpha 4b / CHRNA4* / O70174* / P43681* / cholinergic receptor nicotinic alpha 4 subunit* / cholinergic receptor, nicotinic, alpha polypeptide 4*ENSDARG0000007072443
chrna3 / cholinergic receptor, nicotinic, alpha 3 / P32297* / cholinergic receptor nicotinic alpha 3 subunit* / cholinergic receptor, nicotinic, alpha polypeptide 3*ENSDARG0000010099141
chrna6 / cholinergic receptor, nicotinic, alpha 6 / Q15825* / Q9R0W9* / cholinergic receptor nicotinic alpha 6 subunit* / cholinergic receptor, nicotinic, alpha polypeptide 6*ENSDARG0000005555941
chrna4a / cholinergic receptor, nicotinic, alpha 4a / CHRNA4* / O70174* / P43681* / cholinergic receptor nicotinic alpha 4 subunit* / cholinergic receptor, nicotinic, alpha polypeptide 4*ENSDARG0000008707139
chrnb3a / cholinergic receptor, nicotinic, beta polypeptide 3a / Q8BMN3* / CHRNB3* / Q05901* / cholinergic receptor nicotinic beta 3 subunit* / cholinergic receptor, nicotinic, beta polypeptide 3*ENSDARG0000005276436
chrnb3b / cholinergic receptor, nicotinic, beta 3b (neuronal) / CHRNB3* / Q05901* / Q8BMN3* / cholinergic receptor nicotinic beta 3 subunit* / cholinergic receptor, nicotinic, beta polypeptide 3*ENSDARG0000003850835
chrna5 / cholinergic receptor, nicotinic, alpha 5 / P30532* / Q2MKA5* / cholinergic receptor nicotinic alpha 5 subunit* / cholinergic receptor, nicotinic, alpha polypeptide 5*ENSDARG0000000342034
Q98880 / chrna1 / cholinergic receptor, nicotinic, alpha 1 (muscle) / P02708* / P04756* / cholinergic receptor nicotinic alpha 1 subunit* / cholinergic receptor, nicotinic, alpha polypeptid...ENSDARG0000000902134


Protein motifs (from Interpro)
Interpro ID Name
 IPR002394  Nicotinic acetylcholine receptor
 IPR006029  Neurotransmitter-gated ion-channel transmembrane domain
 IPR006201  Neurotransmitter-gated ion-channel
 IPR006202  Neurotransmitter-gated ion-channel ligand-binding domain
 IPR018000  Neurotransmitter-gated ion-channel, conserved site
 IPR032932  Neuronal acetylcholine receptor subunit beta-2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007271 synaptic transmission, cholinergic IBA
 biological_processGO:0007274 neuromuscular synaptic transmission IBA
 biological_processGO:0034220 ion transmembrane transport IEA
 biological_processGO:0035094 response to nicotine IBA
 biological_processGO:0060078 regulation of postsynaptic membrane potential IEA
 biological_processGO:0060079 excitatory postsynaptic potential IEA
 biological_processGO:0098655 cation transmembrane transport IBA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005892 acetylcholine-gated channel complex IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0045211 postsynaptic membrane IEA
 molecular_functionGO:0004888 transmembrane signaling receptor activity IEA
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005230 extracellular ligand-gated ion channel activity IEA
 molecular_functionGO:0022848 acetylcholine-gated cation-selective channel activity IBA
 molecular_functionGO:0042166 acetylcholine binding IBA


Pathways (from Reactome)
Pathway description
Highly sodium permeable acetylcholine nicotinic receptors
Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
Highly calcium permeable nicotinic acetylcholine receptors


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000017790 chrnb2b / cholinergic receptor, nicotinic, beta 2b / CHRNB2* / P17787* / Q9ERK7* / cholinergic receptor nicotinic beta 2 subunit* / cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal)*  / complex
 ENSDARG00000003420 chrna5 / cholinergic receptor, nicotinic, alpha 5 / P30532* / Q2MKA5* / cholinergic receptor nicotinic alpha 5 subunit* / cholinergic receptor, nicotinic, alpha polypeptide 5*  / complex
 ENSDARG00000070724 chrna4b / cholinergic receptor, nicotinic, alpha 4b / CHRNA4* / O70174* / P43681* / cholinergic receptor nicotinic alpha 4 subunit* / cholinergic receptor, nicotinic, alpha polypeptide 4*  / complex






 

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