ENSGALG00000003005


Gallus gallus

Features
Gene ID: ENSGALG00000003005
  
Biological name :CHRNB4
  
Synonyms : CHRNB4 / neuronal acetylcholine receptor subunit beta-4 precursor
  
Possible biological names infered from orthology : cholinergic receptor nicotinic beta 4 subunit / cholinergic receptor, nicotinic, beta polypeptide 4 / P30926 / Q8R493
  
Species: Gallus gallus
  
Chr. number: 10
Strand: 1
Band:
Gene start: 3543223
Gene end: 3555508
  
Corresponding Affymetrix probe sets: Gga.341.1.S1_at (Chicken Array)   Gga.341.1.S2_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000039014
NCBI entrez gene - 395613     See in Manteia.
RefSeq - NM_204819
RefSeq Peptide - NP_990150
swissprot - F1P4U2
Ensembl - ENSGALG00000003005
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 chrnb4ENSDARG00000101677Danio rerio
 CHRNB4ENSG00000117971Homo sapiens
 Chrnb4ENSMUSG00000035200Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CHRNB2 / neuronal acetylcholine receptor subunit beta-2 precursor / P17787* / Q9ERK7* / cholinergic receptor nicotinic beta 2 subunit* / cholinergic receptor, nicotinic, beta polypeptide 2...ENSGALG0000000270766
CHRNA4 / neuronal acetylcholine receptor subunit alpha-4 precursor / O70174* / P43681* / cholinergic receptor nicotinic alpha 4 subunit* / cholinergic receptor, nicotinic, alpha polypeptide 4*ENSGALG0000000580149
CHRNA2 / neuronal acetylcholine receptor subunit alpha-2 precursor / Q15822* / Q91X60* / cholinergic receptor nicotinic alpha 2 subunit* / cholinergic receptor, nicotinic, alpha polypeptid...ENSGALG0000001656546
CHRNA3 / P09481 / Neuronal acetylcholine receptor subunit alpha-3 / P32297* / cholinergic receptor nicotinic alpha 3 subunit* / cholinergic receptor, nicotinic, alpha polypeptide 3*ENSGALG0000000301444
CHRNA6 / neuronal acetylcholine receptor subunit alpha-6 precursor / Q15825* / Q9R0W9* / cholinergic receptor nicotinic alpha 6 subunit* / cholinergic receptor, nicotinic, alpha polypeptide 6*ENSGALG0000001538244
CHRNA1 / acetylcholine receptor subunit alpha precursor / P02708* / P04756* / cholinergic receptor nicotinic alpha 1 subunit* / cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle)*ENSGALG0000000930139
CHRNA5 / neuronal acetylcholine receptor subunit alpha-5 precursor / P30532* / Q2MKA5* / cholinergic receptor nicotinic alpha 5 subunit* / cholinergic receptor, nicotinic, alpha polypeptide 5*ENSGALG0000000302138
CHRNB3 / cholinergic receptor nicotinic beta 3 subunit / Q05901* / Q8BMN3* / cholinergic receptor, nicotinic, beta polypeptide 3*ENSGALG0000001538438


Protein motifs (from Interpro)
Interpro ID Name
 IPR002394  Nicotinic acetylcholine receptor
 IPR006029  Neurotransmitter-gated ion-channel transmembrane domain
 IPR006201  Neurotransmitter-gated ion-channel
 IPR006202  Neurotransmitter-gated ion-channel ligand-binding domain
 IPR018000  Neurotransmitter-gated ion-channel, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001508 action potential IEA
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006939 smooth muscle contraction IEA
 biological_processGO:0006940 regulation of smooth muscle contraction IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007626 locomotory behavior IEA
 biological_processGO:0034220 ion transmembrane transport IEA
 biological_processGO:0035094 response to nicotine IEA
 biological_processGO:0035095 behavioral response to nicotine IEA
 biological_processGO:0042391 regulation of membrane potential IEA
 biological_processGO:0051971 positive regulation of transmission of nerve impulse IEA
 biological_processGO:0060078 regulation of postsynaptic membrane potential IEA
 biological_processGO:0060079 excitatory postsynaptic potential IEA
 biological_processGO:0060084 synaptic transmission involved in micturition IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005892 acetylcholine-gated channel complex IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0045211 postsynaptic membrane IEA
 molecular_functionGO:0004888 transmembrane signaling receptor activity IEA
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005230 extracellular ligand-gated ion channel activity IEA
 molecular_functionGO:0015464 acetylcholine receptor activity IEA
 molecular_functionGO:0022848 acetylcholine-gated cation-selective channel activity IEA


Pathways (from Reactome)
Pathway description
Highly sodium permeable acetylcholine nicotinic receptors
Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
Highly calcium permeable nicotinic acetylcholine receptors
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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