ENSGALG00000003014


Gallus gallus

Features
Gene ID: ENSGALG00000003014
  
Biological name :CHRNA3
  
Synonyms : CHRNA3 / Neuronal acetylcholine receptor subunit alpha-3 / P09481
  
Possible biological names infered from orthology : cholinergic receptor nicotinic alpha 3 subunit / cholinergic receptor, nicotinic, alpha polypeptide 3 / P32297
  
Species: Gallus gallus
  
Chr. number: 10
Strand: 1
Band:
Gene start: 3561047
Gene end: 3566864
  
Corresponding Affymetrix probe sets: Gga.5095.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000004750
NCBI entrez gene - 386578     See in Manteia.
RefSeq - NM_204416
RefSeq Peptide - NP_989747
swissprot - P09481
Ensembl - ENSGALG00000003014
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 chrna3ENSDARG00000100991Danio rerio
 CHRNA3ENSG00000080644Homo sapiens
 Chrna3ENSMUSG00000032303Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CHRNA6 / neuronal acetylcholine receptor subunit alpha-6 precursor / Q15825* / Q9R0W9* / cholinergic receptor nicotinic alpha 6 subunit* / cholinergic receptor, nicotinic, alpha polypeptide 6*ENSGALG0000001538262
CHRNA4 / neuronal acetylcholine receptor subunit alpha-4 precursor / O70174* / P43681* / cholinergic receptor nicotinic alpha 4 subunit* / cholinergic receptor, nicotinic, alpha polypeptide 4*ENSGALG0000000580155
CHRNA2 / neuronal acetylcholine receptor subunit alpha-2 precursor / Q15822* / Q91X60* / cholinergic receptor nicotinic alpha 2 subunit* / cholinergic receptor, nicotinic, alpha polypeptid...ENSGALG0000001656555
CHRNA1 / acetylcholine receptor subunit alpha precursor / P02708* / P04756* / cholinergic receptor nicotinic alpha 1 subunit* / cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle)*ENSGALG0000000930145
CHRNA5 / neuronal acetylcholine receptor subunit alpha-5 precursor / P30532* / Q2MKA5* / cholinergic receptor nicotinic alpha 5 subunit* / cholinergic receptor, nicotinic, alpha polypeptide 5*ENSGALG0000000302144
CHRNB4 / neuronal acetylcholine receptor subunit beta-4 precursor / P30926* / Q8R493* / cholinergic receptor nicotinic beta 4 subunit* / cholinergic receptor, nicotinic, beta polypeptide 4*ENSGALG0000000300544
CHRNB2 / neuronal acetylcholine receptor subunit beta-2 precursor / P17787* / Q9ERK7* / cholinergic receptor nicotinic beta 2 subunit* / cholinergic receptor, nicotinic, beta polypeptide 2...ENSGALG0000000270744
CHRNB3 / cholinergic receptor nicotinic beta 3 subunit / Q05901* / Q8BMN3* / cholinergic receptor, nicotinic, beta polypeptide 3*ENSGALG0000001538443


Protein motifs (from Interpro)
Interpro ID Name
 IPR002394  Nicotinic acetylcholine receptor
 IPR006029  Neurotransmitter-gated ion-channel transmembrane domain
 IPR006201  Neurotransmitter-gated ion-channel
 IPR006202  Neurotransmitter-gated ion-channel ligand-binding domain
 IPR018000  Neurotransmitter-gated ion-channel, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0034220 ion transmembrane transport IEA
 biological_processGO:0035095 behavioral response to nicotine IEA
 biological_processGO:0060078 regulation of postsynaptic membrane potential IEA
 biological_processGO:0060079 excitatory postsynaptic potential IEA
 biological_processGO:0060084 synaptic transmission involved in micturition IEA
 biological_processGO:0098655 cation transmembrane transport IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005892 acetylcholine-gated channel complex IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0045211 postsynaptic membrane IEA
 molecular_functionGO:0004888 transmembrane signaling receptor activity IEA
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005230 extracellular ligand-gated ion channel activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0015464 acetylcholine receptor activity IEA
 molecular_functionGO:0022848 acetylcholine-gated cation-selective channel activity IEA
 molecular_functionGO:0022850 serotonin-gated cation-selective channel activity IBA


Pathways (from Reactome)
Pathway description
Highly sodium permeable acetylcholine nicotinic receptors
Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
Highly calcium permeable nicotinic acetylcholine receptors


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000003014 CHRNA3 / P09481 / Neuronal acetylcholine receptor subunit alpha-3 / P32297* / cholinergic receptor nicotinic alpha 3 subunit* / cholinergic receptor, nicotinic, alpha polypeptide 3*  / complex
 ENSGALG00000007906 CHRNG / cholinergic receptor nicotinic gamma subunit / P07510* / cholinergic receptor, nicotinic, gamma polypeptide*  / complex






 

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