ENSGALG00000002944


Gallus gallus

Features
Gene ID: ENSGALG00000002944
  
Biological name :CPS1
  
Synonyms : carbamoyl-phosphate synthase / CPS1
  
Possible biological names infered from orthology : carbamoyl-phosphate synthase 1 / Carbamoyl-phosphate synthase [ammonia], mitochondrial / P31327 / Q8C196
  
Species: Gallus gallus
  
Chr. number: 7
Strand: 1
Band:
Gene start: 2817507
Gene end: 2918510
  
Corresponding Affymetrix probe sets: Gga.2653.1.S1_at (Chicken Array)   GgaAffx.1879.1.S1_at (Chicken Array)   GgaAffx.1952.1.S1_at (Chicken Array)   GgaAffx.1959.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000004647
NCBI entrez gene - 428994     See in Manteia.
RefSeq - NM_001045841
RefSeq - XM_015289176
RefSeq - XM_015289177
RefSeq Peptide - NP_001039306
swissprot - F1N9N8
Ensembl - ENSGALG00000002944
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cps1ENSDARG00000020028Danio rerio
 CPS1ENSG00000021826Homo sapiens
 Cps1ENSMUSG00000025991Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CAD / carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase / B2RQC6* / P27708* / CAD protein Glutamine-dependent carbamoyl-phosphate synthase Aspartate carbamoyl...ENSGALG0000001652452


Protein motifs (from Interpro)
Interpro ID Name
 IPR002474  Carbamoyl-phosphate synthase small subunit, N-terminal domain
 IPR005479  Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain
 IPR005480  Carbamoyl-phosphate synthetase, large subunit oligomerisation domain
 IPR005483  Carbamoyl-phosphate synthase large subunit, CPSase domain
 IPR006274  Carbamoyl-phosphate synthase, small subunit
 IPR006275  Carbamoyl-phosphate synthase, large subunit
 IPR011607  Methylglyoxal synthase-like domain
 IPR011761  ATP-grasp fold
 IPR013815  ATP-grasp fold, subdomain 1
 IPR016185  Pre-ATP-grasp domain superfamily
 IPR017926  Glutamine amidotransferase
 IPR029062  Class I glutamine amidotransferase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000050 urea cycle IBA
 biological_processGO:0006207 "de novo" pyrimidine nucleobase biosynthetic process IEA
 biological_processGO:0006526 arginine biosynthetic process IBA
 biological_processGO:0006541 glutamine metabolic process IEA
 biological_processGO:0006807 nitrogen compound metabolic process IEA
 biological_processGO:0019433 triglyceride catabolic process IEA
 biological_processGO:0032496 response to lipopolysaccharide IEA
 biological_processGO:0042311 vasodilation IEA
 biological_processGO:0046209 nitric oxide metabolic process IEA
 biological_processGO:0050667 homocysteine metabolic process IEA
 biological_processGO:0070409 carbamoyl phosphate biosynthetic process IEA
 biological_processGO:1903718 cellular response to ammonia IEA
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0042645 mitochondrial nucleoid IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004087 carbamoyl-phosphate synthase (ammonia) activity IEA
 molecular_functionGO:0004088 carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity IBA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0072341 modified amino acid binding IEA


Pathways (from Reactome)
Pathway description
Urea cycle


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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