ENSGALG00000003086


Gallus gallus

Features
Gene ID: ENSGALG00000003086
  
Biological name :EXOSC10
  
Synonyms : EXOSC10 / exosome component 10
  
Possible biological names infered from orthology : Mus musculus exosome component 10 (Exosc10), transcript variant 5, mRNA. / P56960 / Q01780
  
Species: Gallus gallus
  
Chr. number: 21
Strand: -1
Band:
Gene start: 4114485
Gene end: 4128598
  
Corresponding Affymetrix probe sets: Gga.2286.1.S1_at (Chicken Array)   Gga.2286.2.S1_at (Chicken Array)   GgaAffx.1945.1.S1_s_at (Chicken Array)   GgaAffx.25739.2.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000004870
NCBI entrez gene - 419454     See in Manteia.
RefSeq - NM_001012730
RefSeq - XM_015296893
RefSeq Peptide - NP_001012748
swissprot - E1C525
Ensembl - ENSGALG00000003086
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 exosc10ENSDARG00000037708Danio rerio
 Q01780ENSG00000171824Homo sapiens
 P56960ENSMUSG00000017264Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR002121  HRDC domain
 IPR002562  3"-5" exonuclease domain
 IPR010997  HRDC-like superfamily
 IPR012337  Ribonuclease H-like superfamily
 IPR012588  Exosome-associated factor Rrp6, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000460 maturation of 5.8S rRNA IEA
 biological_processGO:0000956 nuclear-transcribed mRNA catabolic process IEA
 biological_processGO:0006139 nucleobase-containing compound metabolic process IEA
 biological_processGO:0006396 RNA processing IEA
 biological_processGO:0009048 dosage compensation by inactivation of X chromosome IEA
 biological_processGO:0032211 negative regulation of telomere maintenance via telomerase IEA
 biological_processGO:0044237 cellular metabolic process IEA
 biological_processGO:0071028 nuclear mRNA surveillance IEA
 biological_processGO:0071034 CUT catabolic process IEA
 biological_processGO:0071035 nuclear polyadenylation-dependent rRNA catabolic process IEA
 biological_processGO:0071044 histone mRNA catabolic process IEA
 biological_processGO:0071048 nuclear retention of unspliced pre-mRNA at the site of transcription IEA
 biological_processGO:0090305 nucleic acid phosphodiester bond hydrolysis IEA
 biological_processGO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic IEA
 biological_processGO:1904872 regulation of telomerase RNA localization to Cajal body IEA
 cellular_componentGO:0000176 nuclear exosome (RNase complex) IEA
 cellular_componentGO:0000178 exosome (RNase complex) IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0035327 transcriptionally active chromatin IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0000175 3"-5"-exoribonuclease activity IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004532 exoribonuclease activity IEA
 molecular_functionGO:0008408 3"-5" exonuclease activity IEA


Pathways (from Reactome)
Pathway description
Major pathway of rRNA processing in the nucleolus and cytosol


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000008765 C1D / C1D nuclear receptor corepressor / O35473* / Q13901* / Mus musculus C1D nuclear receptor co-repressor (C1d), transcript variant 2, mRNA.*  / complex
 ENSGALG00000031983 MPHOSPH6 / M-phase phosphoprotein 6 / Q99547* / Q9D1Q1* / Mus musculus M phase phosphoprotein 6 (Mphosph6), transcript variant 3, mRNA.*  / complex






 

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