ENSGALG00000003108


Gallus gallus

Features
Gene ID: ENSGALG00000003108
  
Biological name :SMG6
  
Synonyms : SMG6 / SMG6, nonsense mediated mRNA decay factor
  
Possible biological names infered from orthology : P61406 / Q86US8 / Smg-6 homolog, nonsense mediated mRNA decay factor (C. elegans)
  
Species: Gallus gallus
  
Chr. number: 19
Strand: -1
Band:
Gene start: 5527953
Gene end: 5625658
  
Corresponding Affymetrix probe sets: GgaAffx.1957.1.S1_at (Chicken Array)   GgaAffx.2014.1.S1_at (Chicken Array)   GgaAffx.2014.2.S1_s_at (Chicken Array)   GgaAffx.21046.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000005037
Ensembl peptide - ENSGALP00000004899
Ensembl peptide - ENSGALP00000062903
Ensembl peptide - ENSGALP00000051567
NCBI entrez gene - 100857289     See in Manteia.
NCBI entrez gene - 101750600     See in Manteia.
RefSeq - XM_015296050
RefSeq - XM_004946547
RefSeq - XM_004946548
RefSeq - XM_004946553
swissprot - E1C510
swissprot - A0A1L1RVP4
swissprot - A0A1D5PFK0
swissprot - F1NNP8
Ensembl - ENSGALG00000003108
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 smg6ENSDARG00000100481Danio rerio
 SMG6ENSG00000070366Homo sapiens
 Smg6ENSMUSG00000038290Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SMG7 / SMG7, nonsense mediated mRNA decay factor / Q5RJH6* / Q92540* / Protein SMG7 *ENSGALG0000000466713
SMG5 / SMG5, nonsense mediated mRNA decay factor / Q6ZPY2* / Q9UPR3* / Protein SMG5 *ENSGALG0000002991811


Protein motifs (from Interpro)
Interpro ID Name
 IPR002716  PIN domain
 IPR007034  Ribosome biogenesis protein BMS1/TSR1, C-terminal
 IPR011990  Tetratricopeptide-like helical domain superfamily
 IPR012948  AARP2CN
 IPR018834  DNA/RNA-binding domain, Est1-type
 IPR019458  Telomerase activating protein Est1
 IPR029060  PIN-like domain superfamily
 IPR030387  Bms1/Tsr1-type G domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay IEA
 biological_processGO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IBA
 biological_processGO:0000479 endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IBA
 biological_processGO:0006406 mRNA export from nucleus IBA
 biological_processGO:0007004 telomere maintenance via telomerase IBA
 biological_processGO:0032204 regulation of telomere maintenance IEA
 biological_processGO:0042254 ribosome biogenesis IEA
 biological_processGO:0043487 regulation of RNA stability IBA
 biological_processGO:0090501 RNA phosphodiester bond hydrolysis IEA
 biological_processGO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic IEA
 biological_processGO:1904354 negative regulation of telomere capping IEA
 cellular_componentGO:0000333 telomerase catalytic core complex IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005697 telomerase holoenzyme complex IBA
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0030688 preribosome, small subunit precursor IBA
 cellular_componentGO:0035145 exon-exon junction complex IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0003924 GTPase activity IBA
 molecular_functionGO:0004521 endoribonuclease activity IEA
 molecular_functionGO:0004540 ribonuclease activity IBA
 molecular_functionGO:0005525 GTP binding IBA
 molecular_functionGO:0034511 U3 snoRNA binding IBA
 molecular_functionGO:0042162 telomeric DNA binding IEA
 molecular_functionGO:0043021 ribonucleoprotein complex binding IEA
 molecular_functionGO:0070034 telomerase RNA binding IEA
 molecular_functionGO:0070182 DNA polymerase binding IEA


Pathways (from Reactome)
Pathway description
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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