ENSGALG00000003324


Gallus gallus

Features
Gene ID: ENSGALG00000003324
  
Biological name :PRRX1
  
Synonyms : paired mesoderm homeobox protein 1 / PRRX1
  
Possible biological names infered from orthology : P54821 / P63013 / paired related homeobox 1
  
Species: Gallus gallus
  
Chr. number: 8
Strand: -1
Band:
Gene start: 4848542
Gene end: 4880892
  
Corresponding Affymetrix probe sets: Gga.1546.1.S1_at (Chicken Array)   Gga.1546.1.S1_a_at (Chicken Array)   Gga.1546.1.S2_a_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000005255
Ensembl peptide - ENSGALP00000064163
Ensembl peptide - ENSGALP00000060137
Ensembl peptide - ENSGALP00000058661
Ensembl peptide - ENSGALP00000056263
NCBI entrez gene - 373941     See in Manteia.
RefSeq - XM_015290231
RefSeq - NM_001007821
RefSeq - NM_001277724
RefSeq - XM_015290230
RefSeq Peptide - NP_001007822
RefSeq Peptide - NP_001264653
swissprot - A0A1L1RZ65
swissprot - G1K2Z3
swissprot - A0A1L1RMY9
swissprot - A0A1L1RIT7
swissprot - A0A1D5PTL5
Ensembl - ENSGALG00000003324
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 prrx1aENSDARG00000033971Danio rerio
 prrx1bENSDARG00000042027Danio rerio
 PRRX1ENSG00000116132Homo sapiens
 Prrx1ENSMUSG00000026586Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PRRX2 / paired related homeobox 2 / Q99811*ENSGALG0000002823660
PITX2 / pituitary homeobox 2 / Q99697* / P97474* / paired like homeodomain 2* / paired-like homeodomain transcription factor 2*ENSGALG0000004249229
ENSGALG0000000561328
PITX1 / pituitary homeobox 1 / PITX3* / O35160* / P70314* / O75364* / P78337* / Pituitary homeobox 3 * / paired like homeodomain 1* / paired like homeodomain 3* / paired-like homeodomain t...ENSGALG0000003023727
DMBX1 / diencephalon/mesencephalon homeobox 1 / Q8NFW5* / Q91ZK4* / Diencephalon/mesencephalon homeobox protein 1 *ENSGALG0000001043626
OTX1 / orthodenticle homeobox 1 / P32242* / P80205* / Homeobox protein OTX1 *ENSGALG0000002881724
OTX2 / orthodenticle homeobox 2 / P32243*ENSGALG0000003488923
GSC / homeobox protein goosecoid / P56915* / Q02591* / goosecoid homeobox*ENSGALG0000001097420
GSC2 / goosecoid homeobox 2 / O15499*ENSGALG0000004424518


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR003654  OAR domain
 IPR009057  Homeobox-like domain superfamily
 IPR017970  Homeobox, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0002053 positive regulation of mesenchymal cell proliferation IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0030326 embryonic limb morphogenesis IEA
 biological_processGO:0042472 inner ear morphogenesis IEA
 biological_processGO:0042474 middle ear morphogenesis IEA
 biological_processGO:0045880 positive regulation of smoothened signaling pathway IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0048664 neuron fate determination IEA
 biological_processGO:0048701 embryonic cranial skeleton morphogenesis IEA
 biological_processGO:0048704 embryonic skeletal system morphogenesis IEA
 biological_processGO:0048844 artery morphogenesis IEA
 biological_processGO:0051216 cartilage development IEA
 biological_processGO:0060021 roof of mouth development IEA
 biological_processGO:0070570 regulation of neuron projection regeneration IEA
 biological_processGO:0097150 neuronal stem cell population maintenance IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0001078 transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA
 molecular_functionGO:0071837 HMG box domain binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr