ENSGALG00000042492


Gallus gallus

Features
Gene ID: ENSGALG00000042492
  
Biological name :PITX2
  
Synonyms : pituitary homeobox 2 / PITX2
  
Possible biological names infered from orthology : P97474 / paired like homeodomain 2 / paired-like homeodomain transcription factor 2 / Q99697
  
Species: Gallus gallus
  
Chr. number: 4
Strand: 1
Band:
Gene start: 58157162
Gene end: 58171834
  
Corresponding Affymetrix probe sets: Gga.3398.1.S1_at (Chicken Array)   Gga.3398.1.S1_a_at (Chicken Array)   Gga.3398.2.S1_a_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000046381
Ensembl peptide - ENSGALP00000063986
Ensembl peptide - ENSGALP00000056629
Ensembl peptide - ENSGALP00000046615
NCBI entrez gene - 395862     See in Manteia.
RefSeq - NM_205010
RefSeq Peptide - NP_990341
swissprot - A0A1L1RYS0
swissprot - A0A1D5P1S6
swissprot - A0A1D5P150
Ensembl - ENSGALG00000042492
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pitx2ENSDARG00000036194Danio rerio
 PITX2ENSG00000164093Homo sapiens
 Pitx2ENSMUSG00000028023Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ENSGALG0000000561365
PITX1 / pituitary homeobox 1 / PITX3* / O35160* / P70314* / O75364* / P78337* / Pituitary homeobox 3 * / paired like homeodomain 1* / paired like homeodomain 3* / paired-like homeodomain t...ENSGALG0000003023761
DMBX1 / diencephalon/mesencephalon homeobox 1 / Q8NFW5* / Q91ZK4* / Diencephalon/mesencephalon homeobox protein 1 *ENSGALG0000001043624
PRRX1 / paired mesoderm homeobox protein 1 / P54821* / P63013* / paired related homeobox 1*ENSGALG0000000332422
PRRX2 / paired related homeobox 2 / Q99811*ENSGALG0000002823622
OTX2 / orthodenticle homeobox 2 / P32243*ENSGALG0000003488922
OTX1 / orthodenticle homeobox 1 / P32242* / P80205* / Homeobox protein OTX1 *ENSGALG0000002881720
GSC2 / goosecoid homeobox 2 / O15499*ENSGALG0000004424514
GSC / homeobox protein goosecoid / P56915* / Q02591* / goosecoid homeobox*ENSGALG0000001097414


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR003654  OAR domain
 IPR009057  Homeobox-like domain superfamily
 IPR016233  Homeobox protein Pitx/unc30
 IPR017970  Homeobox, conserved site
 IPR020479  Homeobox domain, metazoa


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001569 branching involved in blood vessel morphogenesis IEA
 biological_processGO:0001570 vasculogenesis IEA
 biological_processGO:0001701 in utero embryonic development IEA
 biological_processGO:0001764 neuron migration IEA
 biological_processGO:0002074 extraocular skeletal muscle development IEA
 biological_processGO:0003171 atrioventricular valve development IEA
 biological_processGO:0003253 cardiac neural crest cell migration involved in outflow tract morphogenesis IEA
 biological_processGO:0003350 pulmonary myocardium development IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007368 determination of left/right symmetry IEA
 biological_processGO:0007507 heart development IEA
 biological_processGO:0007519 skeletal muscle tissue development IEA
 biological_processGO:0007520 myoblast fusion IEA
 biological_processGO:0009653 anatomical structure morphogenesis IEA
 biological_processGO:0009887 animal organ morphogenesis IEA
 biological_processGO:0016055 Wnt signaling pathway IEA
 biological_processGO:0021763 subthalamic nucleus development IEA
 biological_processGO:0021855 hypothalamus cell migration IEA
 biological_processGO:0021983 pituitary gland development IEA
 biological_processGO:0030324 lung development IEA
 biological_processGO:0030334 regulation of cell migration IEA
 biological_processGO:0031076 embryonic camera-type eye development IEA
 biological_processGO:0035116 embryonic hindlimb morphogenesis IEA
 biological_processGO:0035886 vascular smooth muscle cell differentiation IEA
 biological_processGO:0035993 deltoid tuberosity development IEA
 biological_processGO:0042127 regulation of cell proliferation IEA
 biological_processGO:0042476 odontogenesis IEA
 biological_processGO:0043010 camera-type eye development IEA
 biological_processGO:0043388 positive regulation of DNA binding IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0048536 spleen development IEA
 biological_processGO:0048557 embryonic digestive tract morphogenesis IEA
 biological_processGO:0048738 cardiac muscle tissue development IEA
 biological_processGO:0055007 cardiac muscle cell differentiation IEA
 biological_processGO:0055009 atrial cardiac muscle tissue morphogenesis IEA
 biological_processGO:0055015 ventricular cardiac muscle cell development IEA
 biological_processGO:0055123 digestive system development IEA
 biological_processGO:0060412 ventricular septum morphogenesis IEA
 biological_processGO:0060460 left lung morphogenesis IEA
 biological_processGO:0060577 pulmonary vein morphogenesis IEA
 biological_processGO:0060578 superior vena cava morphogenesis IEA
 biological_processGO:0061031 endodermal digestive tract morphogenesis IEA
 biological_processGO:0061072 iris morphogenesis IEA
 biological_processGO:0061325 cell proliferation involved in outflow tract morphogenesis IEA
 biological_processGO:0070986 left/right axis specification IEA
 biological_processGO:2000288 positive regulation of myoblast proliferation IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005667 transcription factor complex IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0000976 transcription regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding IEA
 molecular_functionGO:0001102 RNA polymerase II activating transcription factor binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003682 chromatin binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0008134 transcription factor binding IEA
 molecular_functionGO:0031490 chromatin DNA binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr