ENSGALG00000003365


Gallus gallus

Features
Gene ID: ENSGALG00000003365
  
Biological name :RAD1
  
Synonyms : RAD1 / RAD1 checkpoint DNA exonuclease
  
Possible biological names infered from orthology : Cell cycle checkpoint protein RAD1 / O60671 / Q9QWZ1
  
Species: Gallus gallus
  
Chr. number: Z
Strand: -1
Band:
Gene start: 10557699
Gene end: 10563478
  
Corresponding Affymetrix probe sets: Gga.12669.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000005311
Ensembl peptide - ENSGALP00000064054
Ensembl peptide - ENSGALP00000059995
Ensembl peptide - ENSGALP00000055891
NCBI entrez gene - 427432     See in Manteia.
RefSeq - XM_004937180
RefSeq - XM_425004
swissprot - E1C4I3
swissprot - A0A1L1RYY2
swissprot - A0A1D5PSK5
Ensembl - ENSGALG00000003365
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rad1ENSDARG00000040559Danio rerio
 RAD1ENSG00000113456Homo sapiens
 Rad1ENSMUSG00000022248Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR003011  Cell cycle checkpoint protein, Rad1
 IPR003021  Rad1/Rec1/Rad17


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000077 DNA damage checkpoint IBA
 biological_processGO:0006281 DNA repair IBA
 biological_processGO:0051598 meiotic recombination checkpoint IEA
 biological_processGO:0071479 cellular response to ionizing radiation IEA
 biological_processGO:0090305 nucleic acid phosphodiester bond hydrolysis IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0030896 checkpoint clamp complex IBA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 molecular_functionGO:0003684 damaged DNA binding IBA
 molecular_functionGO:0008408 3"-5" exonuclease activity IBA


Pathways (from Reactome)
Pathway description
Activation of ATR in response to replication stress
HDR through Single Strand Annealing (SSA)
Processing of DNA double-strand break ends
Presynaptic phase of homologous DNA pairing and strand exchange


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000000734 RPA2 / RPA4* / Q13156* / P15927* / replication protein A2* / replication protein A4*  / reaction / complex
 ENSGALG00000003072 RPA1 / Q5ZJJ2 / Replication protein A 70 kDa DNA-binding subunit / Q8VEE4* / P27694* / replication protein A1*  / complex / reaction
 ENSGALG00000010700 RPA3 / replication protein A3 / P35244* / Q9CQ71* / Replication protein A 14 kDa subunit *  / complex / reaction
 ENSGALG00000039589 HUS1* / HUS1B* / Q8NHY5* / O60921* / Q8K572* / Q8BQY8* / Checkpoint protein HUS1 * / Checkpoint protein HUS1B * / HUS1 checkpoint clamp component* / HUS1 checkpoint clamp component B*  / complex






 

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