ENSDARG00000040559


Danio rerio

Features
Gene ID: ENSDARG00000040559
  
Biological name :rad1
  
Synonyms : rad1 / RAD1 homolog (S. pombe)
  
Possible biological names infered from orthology : Cell cycle checkpoint protein RAD1 / O60671 / Q9QWZ1 / RAD1 checkpoint DNA exonuclease
  
Species: Danio rerio
  
Chr. number: 15
Strand: -1
Band:
Gene start: 23776417
Gene end: 23784600
  
Corresponding Affymetrix probe sets: Dr.12498.1.S1_at (Zebrafish Array)   NM_200898_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000059353
Ensembl peptide - ENSDARP00000147311
NCBI entrez gene - 393872     See in Manteia.
RefSeq - NM_200898
RefSeq Peptide - NP_957192
swissprot - Q6P2T4
ZFIN ID - ZDB-GENE-040426-1873
Ensembl - ENSDARG00000040559
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 RAD1ENSGALG00000003365Gallus gallus
 RAD1ENSG00000113456Homo sapiens
 Rad1ENSMUSG00000022248Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR003011  Cell cycle checkpoint protein, Rad1
 IPR003021  Rad1/Rec1/Rad17


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000077 DNA damage checkpoint IBA
 biological_processGO:0006281 DNA repair IBA
 biological_processGO:0090305 nucleic acid phosphodiester bond hydrolysis IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0030896 checkpoint clamp complex IBA
 molecular_functionGO:0003684 damaged DNA binding IBA
 molecular_functionGO:0008408 3"-5" exonuclease activity IBA


Pathways (from Reactome)
Pathway description
Activation of ATR in response to replication stress
HDR through Single Strand Annealing (SSA)
Processing of DNA double-strand break ends
Regulation of TP53 Activity through Phosphorylation
G2/M DNA damage checkpoint


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000003938 rpa1 / Q6NY74 / replication protein A1 / Q8VEE4* / P27694* / Replication protein A 70 kDa DNA-binding subunit *  / complex / reaction
 ENSDARG00000037188 rpa2 / replication protein A2 / RPA4* / Q13156* / P15927* / replication protein A4*  / reaction / complex
 ENSDARG00000056984 rad9a / RAD9 checkpoint clamp component A / Q99638* / Q9Z0F6* / Cell cycle checkpoint control protein RAD9A *  / complex
 ENSDARG00000075632 rad9b / RAD9 checkpoint clamp component B / Q6WBX7* / Q6WBX8*  / complex






 

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