ENSDARG00000056984


Danio rerio

Features
Gene ID: ENSDARG00000056984
  
Biological name :rad9a
  
Synonyms : rad9a / RAD9 checkpoint clamp component A
  
Possible biological names infered from orthology : Cell cycle checkpoint control protein RAD9A / Q99638 / Q9Z0F6
  
Species: Danio rerio
  
Chr. number: 14
Strand: -1
Band:
Gene start: 21923741
Gene end: 21932403
  
Corresponding Affymetrix probe sets: Dr.21055.1.S1_at (Zebrafish Array)   NM_200207_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000054419
NCBI entrez gene - 393176     See in Manteia.
RefSeq - NM_200207
RefSeq Peptide - NP_956501
swissprot - F2Z4U5
ZFIN ID - ZDB-GENE-040426-935
Ensembl - ENSDARG00000056984
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 RAD9AENSG00000172613Homo sapiens
 Rad9aENSMUSG00000024824Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
rad9b / RAD9 checkpoint clamp component B / Q6WBX7* / Q6WBX8*ENSDARG0000007563236


Protein motifs (from Interpro)
Interpro ID Name
 IPR007268  Rad9/Ddc1
 IPR026584  Rad9


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000075 cell cycle checkpoint IEA
 biological_processGO:0000076 DNA replication checkpoint IBA
 biological_processGO:0000077 DNA damage checkpoint IEA
 biological_processGO:0006281 DNA repair IBA
 biological_processGO:0031573 intra-S DNA damage checkpoint IBA
 biological_processGO:0071479 cellular response to ionizing radiation IBA
 biological_processGO:0090305 nucleic acid phosphodiester bond hydrolysis IBA
 cellular_componentGO:0030896 checkpoint clamp complex IBA
 molecular_functionGO:0008408 3"-5" exonuclease activity IBA


Pathways (from Reactome)
Pathway description
Activation of ATR in response to replication stress
HDR through Single Strand Annealing (SSA)
Processing of DNA double-strand break ends
Regulation of TP53 Activity through Phosphorylation
G2/M DNA damage checkpoint


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000003938 rpa1 / Q6NY74 / replication protein A1 / Q8VEE4* / P27694* / Replication protein A 70 kDa DNA-binding subunit *  / complex / reaction
 ENSDARG00000037188 rpa2 / replication protein A2 / RPA4* / Q13156* / P15927* / replication protein A4*  / complex / reaction
 ENSDARG00000040559 rad1 / RAD1 homolog (S. pombe) / Q9QWZ1* / O60671* / RAD1 checkpoint DNA exonuclease* / Cell cycle checkpoint protein RAD1 *  / complex






 

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