ENSDARG00000075632


Danio rerio

Features
Gene ID: ENSDARG00000075632
  
Biological name :rad9b
  
Synonyms : rad9b / RAD9 checkpoint clamp component B
  
Possible biological names infered from orthology : Q6WBX7 / Q6WBX8
  
Species: Danio rerio
  
Chr. number: 8
Strand: -1
Band:
Gene start: 4407994
Gene end: 4431985
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000113875
Ensembl peptide - ENSDARP00000121853
NCBI entrez gene - 563903     See in Manteia.
swissprot - B0S508
swissprot - B0S509
ZFIN ID - ZDB-GENE-040910-3
Ensembl - ENSDARG00000075632
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 RAD9BENSG00000151164Homo sapiens
 Rad9bENSMUSG00000038569Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
rad9a / RAD9 checkpoint clamp component A / Q99638* / Q9Z0F6* / Cell cycle checkpoint control protein RAD9A *ENSDARG0000005698434


Protein motifs (from Interpro)
Interpro ID Name
 IPR007268  Rad9/Ddc1
 IPR026584  Rad9


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000075 cell cycle checkpoint IEA
 biological_processGO:0000076 DNA replication checkpoint IBA
 biological_processGO:0000077 DNA damage checkpoint IEA
 biological_processGO:0006281 DNA repair IBA
 biological_processGO:0031573 intra-S DNA damage checkpoint IBA
 biological_processGO:0071479 cellular response to ionizing radiation IBA
 biological_processGO:0090305 nucleic acid phosphodiester bond hydrolysis IBA
 cellular_componentGO:0030896 checkpoint clamp complex IEA
 molecular_functionGO:0008408 3"-5" exonuclease activity IBA


Pathways (from Reactome)
Pathway description
Activation of ATR in response to replication stress
HDR through Single Strand Annealing (SSA)
Processing of DNA double-strand break ends
Regulation of TP53 Activity through Phosphorylation
G2/M DNA damage checkpoint


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000003938 rpa1 / Q6NY74 / replication protein A1 / Q8VEE4* / P27694* / Replication protein A 70 kDa DNA-binding subunit *  / reaction / complex
 ENSDARG00000037188 rpa2 / replication protein A2 / RPA4* / Q13156* / P15927* / replication protein A4*  / reaction / complex
 ENSDARG00000040559 rad1 / RAD1 homolog (S. pombe) / Q9QWZ1* / O60671* / RAD1 checkpoint DNA exonuclease* / Cell cycle checkpoint protein RAD1 *  / complex






 

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