ENSG00000151164


Homo sapiens

Features
Gene ID: ENSG00000151164
  
Biological name :RAD9B
  
Synonyms : Q6WBX8 / RAD9B / RAD9 checkpoint clamp component B
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: 1
Band: q24.11
Gene start: 110501655
Gene end: 110532086
  
Corresponding Affymetrix probe sets: 1553285_s_at (Human Genome U133 Plus 2.0 Array)   1564688_a_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000386434
Ensembl peptide - ENSP00000376440
Ensembl peptide - ENSP00000386629
Ensembl peptide - ENSP00000387329
Ensembl peptide - ENSP00000386697
Ensembl peptide - ENSP00000350777
NCBI entrez gene - 144715     See in Manteia.
OMIM - 608368
RefSeq - XM_017018882
RefSeq - NM_001286534
RefSeq - NM_001286535
RefSeq - NM_001286536
RefSeq - NM_152442
RefSeq - XM_005253849
RefSeq - XM_011537971
RefSeq - XM_011537972
RefSeq - XM_011537974
RefSeq - XM_017018877
RefSeq - XM_017018878
RefSeq - XM_017018879
RefSeq - XM_017018880
RefSeq - XM_017018881
RefSeq - NM_001286531
RefSeq - NM_001286532
RefSeq - NM_001286533
RefSeq Peptide - NP_001273461
RefSeq Peptide - NP_001273462
RefSeq Peptide - NP_001273463
RefSeq Peptide - NP_001273464
RefSeq Peptide - NP_001273465
RefSeq Peptide - NP_689655
RefSeq Peptide - NP_001273460
swissprot - B4DX60
swissprot - H7BY23
swissprot - J3KPN7
swissprot - A0A024RBN9
swissprot - B4DYM6
swissprot - Q6WBX8
Ensembl - ENSG00000151164
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rad9bENSDARG00000075632Danio rerio
 Rad9bENSMUSG00000038569Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RAD9A / Q99638 / RAD9 checkpoint clamp component AENSG0000017261331


Protein motifs (from Interpro)
Interpro ID Name
 IPR007268  Rad9/Ddc1
 IPR026584  Rad9


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000075 cell cycle checkpoint IEA
 biological_processGO:0000076 DNA replication checkpoint IBA
 biological_processGO:0000077 DNA damage checkpoint IEA
 biological_processGO:0006260 DNA replication TAS
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0031573 intra-S DNA damage checkpoint IBA
 biological_processGO:0071479 cellular response to ionizing radiation IBA
 biological_processGO:0090305 nucleic acid phosphodiester bond hydrolysis IBA
 biological_processGO:1901796 regulation of signal transduction by p53 class mediator TAS
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0030896 checkpoint clamp complex IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008408 3"-5" exonuclease activity IBA


Pathways (from Reactome)
Pathway description
Activation of ATR in response to replication stress
HDR through Single Strand Annealing (SSA)
Processing of DNA double-strand break ends
Presynaptic phase of homologous DNA pairing and strand exchange
Regulation of TP53 Activity through Phosphorylation
G2/M DNA damage checkpoint


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000106399 RPA3 / P35244 / replication protein A3  / complex / reaction
 ENSG00000132383 RPA1 / P27694 / replication protein A1  / reaction / complex
 ENSG00000117748 RPA2 / P15927 / replication protein A2  / reaction / complex
 ENSG00000136273 HUS1 / O60921 / HUS1 checkpoint clamp component  / complex
 ENSG00000113456 RAD1 / O60671 / RAD1 checkpoint DNA exonuclease  / complex






 

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