ENSGALG00000003391


Gallus gallus

Features
Gene ID: ENSGALG00000003391
  
Biological name :EIF2AK1
  
Synonyms : EIF2AK1 / eukaryotic translation initiation factor 2-alpha kinase 1
  
Possible biological names infered from orthology : Q9BQI3 / Q9Z2R9
  
Species: Gallus gallus
  
Chr. number: 14
Strand: 1
Band:
Gene start: 960221
Gene end: 976442
  
Corresponding Affymetrix probe sets: Gga.3983.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000005347
NCBI entrez gene - 395360     See in Manteia.
RefSeq - XM_015294131
RefSeq - NM_204648
RefSeq - XM_015294129
RefSeq - XM_015294130
RefSeq Peptide - NP_989979
swissprot - F1NSR6
Ensembl - ENSGALG00000003391
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 eif2ak1ENSDARG00000093182Danio rerio
 Q9BQI3ENSG00000086232Homo sapiens
 Q9Z2R9ENSMUSG00000029613Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
EIF2AK3 / eukaryotic translation initiation factor 2 alpha kinase 3 / Q9NZJ5*ENSGALG0000001595823
EIF2AK4 / eukaryotic translation initiation factor 2 alpha kinase 4 / Q9P2K8* / Q9QZ05* / eIF-2-alpha kinase GCN2 *ENSGALG0000000961121
EIF2AK2 / interferon-induced, double-stranded RNA-activated protein kinase / P19525* / Q03963* / eukaryotic translation initiation factor 2 alpha kinase 2*ENSGALG0000001056015


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002526 acute inflammatory response IEA
 biological_processGO:0006417 regulation of translation IEA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0006909 phagocytosis IEA
 biological_processGO:0008285 negative regulation of cell proliferation IEA
 biological_processGO:0010998 regulation of translational initiation by eIF2 alpha phosphorylation IEA
 biological_processGO:0010999 regulation of eIF2 alpha phosphorylation by heme IEA
 biological_processGO:0030225 macrophage differentiation IEA
 biological_processGO:0046501 protoporphyrinogen IX metabolic process IEA
 biological_processGO:0046777 protein autophosphorylation IEA
 biological_processGO:0046984 regulation of hemoglobin biosynthetic process IEA
 biological_processGO:0046986 negative regulation of hemoglobin biosynthetic process IEA
 biological_processGO:0055072 iron ion homeostasis IEA
 biological_processGO:1990641 response to iron ion starvation IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004694 eukaryotic translation initiation factor 2alpha kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0020037 heme binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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