ENSGALG00000003475


Gallus gallus

Features
Gene ID: ENSGALG00000003475
  
Biological name :ACLY
  
Synonyms : ACLY / ATP-citrate synthase
  
Possible biological names infered from orthology : ATP citrate lyase / P53396 / Q91V92
  
Species: Gallus gallus
  
Chr. number: 27
Strand: -1
Band:
Gene start: 5123850
Gene end: 5147962
  
Corresponding Affymetrix probe sets: Gga.18859.1.S1_at (Chicken Array)   Gga.2159.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000055831
Ensembl peptide - ENSGALP00000039157
NCBI entrez gene - 395373     See in Manteia.
RefSeq - XM_015299581
RefSeq - XM_015299578
RefSeq - XM_015299579
RefSeq - XM_015299580
RefSeq - NM_001030540
RefSeq - XM_015299569
RefSeq - XM_015299570
RefSeq - XM_015299572
RefSeq - XM_015299573
RefSeq - XM_015299574
RefSeq - XM_015299575
RefSeq - XM_015299576
RefSeq - XM_015299577
RefSeq Peptide - NP_001025711
swissprot - F1P269
swissprot - A0A1D5PSE5
Ensembl - ENSGALG00000003475
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 aclyaENSDARG00000099079Danio rerio
 aclybENSDARG00000055652Danio rerio
 ACLYENSG00000131473Homo sapiens
 AclyENSMUSG00000020917Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SUCLG1 / succinate-CoA ligase alpha subunit / P53597* / Q9WUM5* / Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial *ENSGALG000000159618


Protein motifs (from Interpro)
Interpro ID Name
 IPR002020  Citrate synthase
 IPR003781  CoA-binding
 IPR005811  ATP-citrate lyase/succinyl-CoA ligase
 IPR014608  ATP-citrate synthase
 IPR016040  NAD(P)-binding domain
 IPR016102  Succinyl-CoA synthetase-like
 IPR016142  Citrate synthase-like, large alpha subdomain
 IPR016143  Citrate synthase-like, small alpha subdomain
 IPR017440  ATP-citrate lyase/succinyl-CoA ligase, active site
 IPR017866  Succinyl-CoA synthetase, beta subunit, conserved site
 IPR032263  ATP-citrate synthase, citrate-binding domain
 IPR033847  ATP-citrate lyase/succinyl-CoA ligase, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006085 acetyl-CoA biosynthetic process IEA
 biological_processGO:0006101 citrate metabolic process IEA
 biological_processGO:0006107 oxaloacetate metabolic process IEA
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006633 fatty acid biosynthetic process IBA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0008610 lipid biosynthetic process IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0009346 citrate lyase complex IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0003878 ATP citrate synthase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer IEA
 molecular_functionGO:0048037 cofactor binding IEA


Pathways (from Reactome)
Pathway description
ChREBP activates metabolic gene expression
Neutrophil degranulation
Fatty acyl-CoA biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000003475 ACLY / ATP-citrate synthase / P53396* / Q91V92* / ATP citrate lyase*  / complex






 

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