Manteia

ENSGALG00000003806

Gallus gallus

Features

Gene ID:	ENSGALG00000003806

Biological name :	RHOA

Synonyms :	ras homolog family member A / RHOA

Possible biological names infered from orthology :	4930544G11Rik / P61586 / RIKEN cDNA 4930544G11 gene

Species:	Gallus gallus

Chr. number:	12
Strand:	-1
Band:
Gene start:	2825879
Gene end:	2844268

Corresponding Affymetrix probe sets:	Gga.4963.1.S1_at (Chicken Array) Gga.4963.2.S1_a_at (Chicken Array) GgaAffx.12357.1.S1_s_at (Chicken Array)

Cross references:	Ensembl peptide - ENSGALP00000059122 Ensembl peptide - ENSGALP00000062680 Ensembl peptide - ENSGALP00000061779 Ensembl peptide - ENSGALP00000060397 Ensembl peptide - ENSGALP00000059380 Ensembl peptide - ENSGALP00000033584 Ensembl peptide - ENSGALP00000047073 Ensembl peptide - ENSGALP00000048923 Ensembl peptide - ENSGALP00000051789 NCBI entrez gene - 395442 See in Manteia. RefSeq - NM_204704 RefSeq Peptide - NP_990035 swissprot - A0A1L1RK40 swissprot - A0A1L1RSJ6 swissprot - O93467 swissprot - A0A1D5P320 swissprot - A0A1L1RNP0 Ensembl - ENSGALG00000003806

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
rhoab	ENSDARG00000094673	Danio rerio
RHOA	ENSG00000067560	Homo sapiens
4930544G11Rik	ENSMUSG00000036463	Mus musculus

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
RHOC / Q9PSX7 / Rho-related GTP-binding protein RhoC / Q62159* / P08134* / ras homolog family member C*	ENSGALG00000001569	84
RHOB / ras homolog family member B / P62745* / P62746*	ENSGALG00000016485	76
RND2 / Rho family GTPase 2 / P52198* / Q9QYM5*	ENSGALG00000002804	45
RHOF / ras homolog family member F, filopodia associated / Q8BYP3* / Q9HBH0* / ras homolog family member F (in filopodia)*	ENSGALG00000039724	44
RND3 / Rho family GTPase 3 / P61587* / P61588* / Rho-related GTP-binding protein RhoE *	ENSGALG00000026313	43
	ENSGALG00000044774	40

Protein motifs (from Interpro)

Interpro ID	Name
IPR001806	Small GTPase superfamily
IPR005225	Small GTP-binding protein domain
IPR020849	Small GTPase superfamily, Ras-type
IPR027417	P-loop containing nucleoside triphosphate hydrolase

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0007165	signal transduction	IEA
biological_process	GO:0007264	small GTPase mediated signal transduction	IEA
biological_process	GO:0007266	Rho protein signal transduction	IEA
biological_process	GO:0016477	cell migration	IEA
biological_process	GO:0030334	regulation of cell migration	IEA
biological_process	GO:0031532	actin cytoskeleton reorganization	IEA
biological_process	GO:0032467	positive regulation of cytokinesis	IEA
biological_process	GO:0032956	regulation of actin cytoskeleton organization	IEA
biological_process	GO:0034329	cell junction assembly	IEA
biological_process	GO:0035385	Roundabout signaling pathway	IEA
biological_process	GO:0036089	cleavage furrow formation	IEA
biological_process	GO:0038027	apolipoprotein A-I-mediated signaling pathway	IEA
biological_process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	ISS
biological_process	GO:0043149	stress fiber assembly	IEA
biological_process	GO:0043297	apical junction assembly	IEA
biological_process	GO:0043542	endothelial cell migration	IEA
biological_process	GO:0044319	wound healing, spreading of cells	ISS
biological_process	GO:0045198	establishment of epithelial cell apical/basal polarity	IEA
biological_process	GO:0045666	positive regulation of neuron differentiation	IEA
biological_process	GO:0045792	negative regulation of cell size	IEA
biological_process	GO:0050919	negative chemotaxis	IEA
biological_process	GO:0051493	regulation of cytoskeleton organization	IMP
biological_process	GO:0051496	positive regulation of stress fiber assembly	IEA
biological_process	GO:0060193	positive regulation of lipase activity	IEA
biological_process	GO:0060317	cardiac epithelial to mesenchymal transition	IMP
biological_process	GO:0071222	cellular response to lipopolysaccharide	IEA
biological_process	GO:0071902	positive regulation of protein serine/threonine kinase activity	IEA
biological_process	GO:0090051	negative regulation of cell migration involved in sprouting angiogenesis	IEA
biological_process	GO:0090307	mitotic spindle assembly	IEA
biological_process	GO:0097498	endothelial tube lumen extension	IEA
biological_process	GO:1902766	skeletal muscle satellite cell migration	ISS
biological_process	GO:1903673	mitotic cleavage furrow formation	IEA
biological_process	GO:1990869	cellular response to chemokine	IEA
biological_process	GO:2000290	regulation of myotome development	IMP
biological_process	GO:2000406	positive regulation of T cell migration	IEA
cellular_component	GO:0005622	intracellular	IEA
cellular_component	GO:0005768	endosome	IEA
cellular_component	GO:0005829	cytosol	IEA
cellular_component	GO:0005938	cell cortex	IEA
cellular_component	GO:0016020	membrane	IEA
cellular_component	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane	IEA
cellular_component	GO:0031982	vesicle	IEA
cellular_component	GO:0032154	cleavage furrow	IEA
cellular_component	GO:0043197	dendritic spine	IEA
cellular_component	GO:0043296	apical junction complex	IEA
cellular_component	GO:0071944	cell periphery	IEA
molecular_function	GO:0000166	nucleotide binding	IEA
molecular_function	GO:0003924	GTPase activity	IEA
molecular_function	GO:0005525	GTP binding	IEA
molecular_function	GO:0017022	myosin binding	IEA

Pathways (from Reactome)

Phenotype (from MGI, Zfin or HPO)

Phenotype

Definition

Genetic BG

No match

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

0 s.

External programs and data are copyrighted by and are the property of their respective authors. The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation
		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr