ENSGALG00000003860


Gallus gallus

Features
Gene ID: ENSGALG00000003860
  
Biological name :MID2
  
Synonyms : MID2 / midline 2
  
Possible biological names infered from orthology : Mus musculus midline 2 (Mid2), transcript variant 2, mRNA. / Q9UJV3
  
Species: Gallus gallus
  
Chr. number: 4
Strand: -1
Band:
Gene start: 1738814
Gene end: 1777456
  
Corresponding Affymetrix probe sets: GgaAffx.2408.1.S1_at (Chicken Array)   GgaAffx.2408.2.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000006123
NCBI entrez gene - 422131     See in Manteia.
RefSeq - XM_004940585
RefSeq - XM_015278376
swissprot - F1NCH4
Ensembl - ENSGALG00000003860
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mid2ENSDARG00000034871Danio rerio
 MID2ENSG00000080561Homo sapiens
 Mid2ENSMUSG00000000266Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MID1 / E3 ubiquitin-protein ligase Midline-1 / O15344* / O70583* / midline 1*ENSGALG0000003850468
TRIM9 / tripartite motif containing 9 / Q8C7M3* / Q9C026* / E3 ubiquitin-protein ligase TRIM9 *ENSGALG0000001236724
TRIM36 / tripartite motif containing 36 / Q80WG7* / Q9NQ86* / E3 ubiquitin-protein ligase Trim36 *ENSGALG0000000818824
FSD1L / fibronectin type III and SPRY domain containing 1 like / Q8BYN5* / Q9BXM9* / Mus musculus fibronectin type III and SPRY domain containing 1-like (Fsd1l), transcript variant 3, mRNA.*ENSGALG0000001544218
TRIM67 / tripartite motif containing 67 / Q505D9* / Q6ZTA4* / Tripartite motif-containing protein 67 *ENSGALG0000003096015
TRIM55 / tripartite motif-containing protein 55 / Q9BYV6* / tripartite motif containing 55*ENSGALG0000004132715
TRIM54 / tripartite motif containing 54 / Q9BYV2* / Q9ERP3* / Tripartite motif-containing protein 54 *ENSGALG0000003320313
TRIM63 / tripartite motif containing 63 / Q969Q1*ENSGALG0000003410713
FSD1* / Q7TPM6* / Q9BTV5* / fibronectin type III and SPRY domain containing 1* / Fibronectin type III and SPRY domain-containing protein 1 *ENSGALG000000329384


Protein motifs (from Interpro)
Interpro ID Name
 IPR000315  B-box-type zinc finger
 IPR001841  Zinc finger, RING-type
 IPR001870  B30.2/SPRY domain
 IPR003649  B-box, C-terminal
 IPR003877  SPRY domain
 IPR003879  Butyrophylin-like, SPRY domain
 IPR003961  Fibronectin type III
 IPR006574  SPRY-associated
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR013320  Concanavalin A-like lectin/glucanase domain superfamily
 IPR013783  Immunoglobulin-like fold
 IPR017903  COS domain
 IPR017907  Zinc finger, RING-type, conserved site
 IPR033491  Probable E3 ubiquitin-protein ligase MID2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010508 positive regulation of autophagy IEA
 biological_processGO:0032897 negative regulation of viral transcription IEA
 biological_processGO:0035372 protein localization to microtubule IEA
 biological_processGO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling IEA
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0046597 negative regulation of viral entry into host cell IEA
 biological_processGO:0051091 positive regulation of DNA-binding transcription factor activity IEA
 biological_processGO:0051092 positive regulation of NF-kappaB transcription factor activity IEA
 biological_processGO:1902187 negative regulation of viral release from host cell IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005874 microtubule IEA
 molecular_functionGO:0008017 microtubule binding IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0046982 protein heterodimerization activity IEA
 molecular_functionGO:0051219 phosphoprotein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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