ENSGALG00000004477


Gallus gallus

Features
Gene ID: ENSGALG00000004477
  
Biological name :NCOR1
  
Synonyms : NCOR1 / nuclear receptor corepressor 1
  
Possible biological names infered from orthology : nuclear receptor co-repressor 1 / O75376
  
Species: Gallus gallus
  
Chr. number: 19
Strand: -1
Band:
Gene start: 6466653
Gene end: 6508512
  
Corresponding Affymetrix probe sets: Gga.18223.1.S1_at (Chicken Array)   Gga.2993.1.S1_at (Chicken Array)   Gga.2993.2.S1_a_at (Chicken Array)   GgaAffx.26222.1.A1_at (Chicken Array)   GgaAffx.26222.1.A1_s_at (Chicken Array)   GgaAffx.2770.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000007118
Ensembl peptide - ENSGALP00000056807
Ensembl peptide - ENSGALP00000053274
Ensembl peptide - ENSGALP00000049677
NCBI entrez gene - 417598     See in Manteia.
RefSeq - XM_415843
RefSeq - XM_004946657
RefSeq - XM_004946661
RefSeq - XM_015295826
RefSeq - XM_015295827
RefSeq - XM_004946655
RefSeq - XM_004946656
swissprot - A0A1D5PV47
swissprot - A0A1D5PKB7
swissprot - A0A1D5PAB7
swissprot - E1BSW5
Ensembl - ENSGALG00000004477
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ncor1ENSDARG00000035285Danio rerio
 NCOR1ENSG00000141027Homo sapiens
 Ncor1ENSMUSG00000018501Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NCOR2 / nuclear receptor corepressor 2 / Q9WU42* / Q9Y618*ENSGALG0000000312042
RCOR1 / REST corepressor 1 / Q8CFE3* / Q9UKL0*ENSGALG000000113844
RCOR3 / REST corepressor 3 / Q6PGA0* / Q9P2K3*ENSGALG000000098714


Protein motifs (from Interpro)
Interpro ID Name
 IPR001005  SANT/Myb domain
 IPR009057  Homeobox-like domain superfamily
 IPR017884  SANT domain
 IPR031557  N-CoR, GPS2-interacting domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0046329 negative regulation of JNK cascade IEA
 biological_processGO:0051225 spindle assembly IEA
 biological_processGO:0072362 regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter IEA
 biological_processGO:0072368 regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter IEA
 biological_processGO:1903799 negative regulation of production of miRNAs involved in gene silencing by miRNA IEA
 cellular_componentGO:0000118 histone deacetylase complex IEA
 cellular_componentGO:0000790 nuclear chromatin IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005876 spindle microtubule IEA
 cellular_componentGO:0016580 Sin3 complex IEA
 cellular_componentGO:0017053 transcriptional repressor complex IEA
 molecular_functionGO:0001102 RNA polymerase II activating transcription factor binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003714 transcription corepressor activity IEA
 molecular_functionGO:0016922 nuclear receptor binding IBA
 molecular_functionGO:0035257 nuclear hormone receptor binding IEA
 molecular_functionGO:0042826 histone deacetylase binding IEA
 molecular_functionGO:0046966 thyroid hormone receptor binding IBA


Pathways (from Reactome)
Pathway description
Downregulation of SMAD2/3:SMAD4 transcriptional activity
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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