ENSDARG00000035285


Danio rerio

Features
Gene ID: ENSDARG00000035285
  
Biological name :ncor1
  
Synonyms : ncor1 / nuclear receptor corepressor 1
  
Possible biological names infered from orthology : nuclear receptor co-repressor 1 / O75376
  
Species: Danio rerio
  
Chr. number: 5
Strand: -1
Band:
Gene start: 41878252
Gene end: 41996414
  
Corresponding Affymetrix probe sets: Dr.17363.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000088345
Ensembl peptide - ENSDARP00000120166
Ensembl peptide - ENSDARP00000150307
swissprot - A3QK40
swissprot - F1QWG8
ZFIN ID - ZDB-GENE-040426-993
Ensembl - ENSDARG00000035285
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 NCOR1ENSGALG00000004477Gallus gallus
 NCOR1ENSG00000141027Homo sapiens
 Ncor1ENSMUSG00000018501Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ncor2 / nuclear receptor corepressor 2 / Q9WU42* / Q9Y618*ENSDARG0000000096636
rcor3 / REST corepressor 3 / Q6PGA0* / Q9P2K3*ENSDARG000000045025
rcor2 / Q6P116 / REST corepressor 2 / Q8C796* / Q8IZ40*ENSDARG000000082785
rcor1 / REST corepressor 1 / Q8CFE3* / Q9UKL0*ENSDARG000000314344


Protein motifs (from Interpro)
Interpro ID Name
 IPR001005  SANT/Myb domain
 IPR009057  Homeobox-like domain superfamily
 IPR017884  SANT domain
 IPR031557  N-CoR, GPS2-interacting domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IBA
 biological_processGO:0009952 anterior/posterior pattern specification IMP
 biological_processGO:0030223 neutrophil differentiation IMP
 biological_processGO:0030902 hindbrain development IMP
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0016580 Sin3 complex IBA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003714 transcription corepressor activity IBA
 molecular_functionGO:0016922 nuclear receptor binding IBA
 molecular_functionGO:0046966 thyroid hormone receptor binding IBA


Pathways (from Reactome)
Pathway description
Downregulation of SMAD2/3:SMAD4 transcriptional activity
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000029 hindbrain hindbrain decreased length , abnormal
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 ZFA:0001094 whole organism whole organism wholly posterioralized , abnormal
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 ZFA:0009141 macrophage macrophage decreased amount , abnormal
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 ZFA:0009327 neutrophil neutrophil decreased amount , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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