ENSGALG00000005425


Gallus gallus

Features
Gene ID: ENSGALG00000005425
  
Biological name :OGT
  
Synonyms : OGT / O-linked N-acetylglucosamine (GlcNAc) transferase
  
Possible biological names infered from orthology : O15294 / Q8CGY8 / UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit
  
Species: Gallus gallus
  
Chr. number: 4
Strand: -1
Band:
Gene start: 2209876
Gene end: 2231355
  
Corresponding Affymetrix probe sets: Gga.4475.1.S1_at (Chicken Array)   GgaAffx.12237.1.S1_s_at (Chicken Array)   GgaAffx.26501.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000046311
Ensembl peptide - ENSGALP00000060468
Ensembl peptide - ENSGALP00000052262
Ensembl peptide - ENSGALP00000008699
NCBI entrez gene - 422203     See in Manteia.
RefSeq - XM_001232518
RefSeq - XM_004940630
swissprot - A0A1D5PHI3
swissprot - A0A1D5P0Y1
swissprot - F1NX56
swissprot - Q5ZKF0
Ensembl - ENSGALG00000005425
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ogt.1ENSDARG00000105243Danio rerio
 ogt.1ENSDARG00000099455Danio rerio
 OGTENSG00000147162Homo sapiens
 OgtENSMUSG00000034160Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TMTC4 / transmembrane and tetratricopeptide repeat containing 4 / Q5T4D3* / Q8BG19* / Transmembrane and TPR repeat-containing protein 4 *ENSGALG0000001687012
TMTC1 / transmembrane and tetratricopeptide repeat containing 1 / Q3UV71* / Q8IUR5* / Mus musculus transmembrane and tetratricopeptide repeat containing 1 (Tmtc1), transcript variant 2, mRNA.*ENSGALG0000001295612
TMTC2 / transmembrane and tetratricopeptide repeat containing 2 / Q56A06* / Q8N394*ENSGALG0000001097511
TMTC3* / Q6ZXV5* / transmembrane and tetratricopeptide repeat containing 3*ENSGALG000000111988
TMTC3* / Q6ZXV5* / transmembrane and tetratricopeptide repeat containing 3*ENSGALG000000331064


Protein motifs (from Interpro)
Interpro ID Name
 IPR001440  Tetratricopeptide repeat 1
 IPR011717  Tetratricopeptide TPR-4
 IPR011990  Tetratricopeptide-like helical domain superfamily
 IPR013026  Tetratricopeptide repeat-containing domain
 IPR019734  Tetratricopeptide repeat
 IPR029489  O-GlcNAc transferase, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006110 regulation of glycolytic process IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006493 protein O-linked glycosylation IEA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0016485 protein processing IEA
 biological_processGO:0031397 negative regulation of protein ubiquitination IEA
 biological_processGO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0032868 response to insulin IEA
 biological_processGO:0032922 circadian regulation of gene expression IEA
 biological_processGO:0035020 regulation of Rac protein signal transduction IEA
 biological_processGO:0043981 histone H4-K5 acetylation IEA
 biological_processGO:0043982 histone H4-K8 acetylation IEA
 biological_processGO:0043984 histone H4-K16 acetylation IEA
 biological_processGO:0045862 positive regulation of proteolysis IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0046626 regulation of insulin receptor signaling pathway IEA
 biological_processGO:0048015 phosphatidylinositol-mediated signaling IEA
 biological_processGO:0061087 positive regulation of histone H3-K27 methylation IEA
 biological_processGO:0080182 histone H3-K4 trimethylation IEA
 cellular_componentGO:0000123 histone acetyltransferase complex IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0032991 protein-containing complex IEA
 molecular_functionGO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding IEA
 molecular_functionGO:0016262 protein N-acetylglucosaminyltransferase activity IEA
 molecular_functionGO:0016757 transferase activity, transferring glycosyl groups IEA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0043995 histone acetyltransferase activity (H4-K5 specific) IEA
 molecular_functionGO:0043996 histone acetyltransferase activity (H4-K8 specific) IEA
 molecular_functionGO:0046972 histone acetyltransferase activity (H4-K16 specific) IEA
 molecular_functionGO:0097363 protein O-GlcNAc transferase activity IEA


Pathways (from Reactome)
Pathway description
HATs acetylate histones
UCH proteinases


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000004460 FOXK1 / forkhead box K1 / P42128* / P85037* / Forkhead box protein K1 *  / complex
 ENSGALG00000006612 ASXL1 / additional sex combs like 1, transcriptional regulator / P59598* / Q8IXJ9* / Putative Polycomb group protein ASXL1 *  / complex
 ENSGALG00000004366 BAP1 / ubiquitin carboxyl-terminal hydrolase BAP1 / Q92560* / Q99PU7* / BRCA1 associated protein 1*  / reaction / complex






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr