ENSGALG00000006612


Gallus gallus

Features
Gene ID: ENSGALG00000006612
  
Biological name :ASXL1
  
Synonyms : additional sex combs like 1, transcriptional regulator / ASXL1
  
Possible biological names infered from orthology : P59598 / Putative Polycomb group protein ASXL1 / Q8IXJ9
  
Species: Gallus gallus
  
Chr. number: 20
Strand: 1
Band:
Gene start: 10358970
Gene end: 10373491
  
Corresponding Affymetrix probe sets: Gga.5222.1.S1_at (Chicken Array)   GgaAffx.21991.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000010661
Ensembl peptide - ENSGALP00000056645
Ensembl peptide - ENSGALP00000053770
NCBI entrez gene - 428158     See in Manteia.
RefSeq - XM_015296597
RefSeq - XM_015296598
swissprot - A0A1D5PUP1
swissprot - A0A1D5PLQ0
swissprot - F1P445
Ensembl - ENSGALG00000006612
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 asxl1ENSDARG00000036956Danio rerio
 ASXL1ENSG00000171456Homo sapiens
 Asxl1ENSMUSG00000042548Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ASXL3 / additional sex combs like 3, transcriptional regulator / Q8C4A5* / Q9C0F0* / Putative Polycomb group protein ASXL3 *ENSGALG0000001519626
ASXL2 / putative Polycomb group protein ASXL2 / Q76L83* / putative Polycomb group protein ASXL2 isoform 1 * / additional sex combs like 2, transcriptional regulator*ENSGALG0000001653124


Protein motifs (from Interpro)
Interpro ID Name
 IPR007759  HB1/Asxl, restriction endonuclease HTH domain
 IPR024811  Polycomb protein ASX/ASX-like
 IPR024815  ASX-like protein 1
 IPR026905  Protein ASX-like, PHD domain
 IPR028020  ASX homology domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000902 cell morphogenesis IEA
 biological_processGO:0003007 heart morphogenesis IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0009887 animal organ morphogenesis IEA
 biological_processGO:0030097 hemopoiesis IEA
 biological_processGO:0032526 response to retinoic acid IEA
 biological_processGO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway IEA
 biological_processGO:0035522 monoubiquitinated histone H2A deubiquitination IEA
 biological_processGO:0045599 negative regulation of fat cell differentiation IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0048386 positive regulation of retinoic acid receptor signaling pathway IEA
 biological_processGO:0048534 hematopoietic or lymphoid organ development IEA
 biological_processGO:0048538 thymus development IEA
 biological_processGO:0048539 bone marrow development IEA
 biological_processGO:0048872 homeostasis of number of cells IEA
 biological_processGO:0060348 bone development IEA
 biological_processGO:0060430 lung saccule development IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0035517 PR-DUB complex IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003713 transcription coactivator activity IEA
 molecular_functionGO:0042974 retinoic acid receptor binding IEA
 molecular_functionGO:0042975 peroxisome proliferator activated receptor binding IEA


Pathways (from Reactome)
Pathway description
UCH proteinases


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000004460 FOXK1 / forkhead box K1 / P42128* / P85037* / Forkhead box protein K1 *  / complex
 ENSGALG00000004366 BAP1 / ubiquitin carboxyl-terminal hydrolase BAP1 / Q92560* / Q99PU7* / BRCA1 associated protein 1*  / reaction / complex
 ENSGALG00000005425 OGT / O-linked N-acetylglucosamine (GlcNAc) transferase / O15294* / Q8CGY8* / UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit *  / complex






 

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